KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
R3HCC1
All Species:
12.12
Human Site:
S139
Identified Species:
38.1
UniProt:
Q9Y3T6
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.29
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y3T6
NP_001129580.1
480
53259
S139
G
P
C
R
A
P
A
S
C
P
S
R
Y
H
G
Chimpanzee
Pan troglodytes
XP_519655
480
53242
S139
G
P
C
R
A
P
A
S
C
P
S
R
Y
H
G
Rhesus Macaque
Macaca mulatta
XP_001108295
498
55172
S158
G
P
C
R
P
P
A
S
Y
P
S
K
Y
H
G
Dog
Lupus familis
XP_534574
452
49550
R135
P
A
G
P
R
G
A
R
A
G
R
G
H
R
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8BSI6
596
65733
S207
G
P
C
R
P
P
A
S
H
P
S
K
Y
R
G
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506902
502
54537
A138
G
P
G
Q
G
H
H
A
K
G
R
S
Q
G
L
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624370
656
74227
A135
E
G
Q
R
S
P
S
A
S
P
E
R
I
R
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_787059
544
60312
K142
A
E
I
S
S
S
S
K
A
L
S
I
E
D
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
90.3
73.3
N.A.
57.2
N.A.
N.A.
56.3
N.A.
N.A.
N.A.
N.A.
N.A.
22.4
N.A.
20.9
Protein Similarity:
100
99.3
92.1
79.1
N.A.
65.4
N.A.
N.A.
64.7
N.A.
N.A.
N.A.
N.A.
N.A.
37.5
N.A.
38.4
P-Site Identity:
100
100
80
13.3
N.A.
73.3
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
6.6
P-Site Similarity:
100
100
86.6
20
N.A.
80
N.A.
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
13
0
0
25
0
63
25
25
0
0
0
0
0
0
% A
% Cys:
0
0
50
0
0
0
0
0
25
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
13
0
% D
% Glu:
13
13
0
0
0
0
0
0
0
0
13
0
13
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
63
13
25
0
13
13
0
0
0
25
0
13
0
13
63
% G
% His:
0
0
0
0
0
13
13
0
13
0
0
0
13
38
0
% H
% Ile:
0
0
13
0
0
0
0
0
0
0
0
13
13
0
13
% I
% Lys:
0
0
0
0
0
0
0
13
13
0
0
25
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
13
0
0
0
0
13
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
13
63
0
13
25
63
0
0
0
63
0
0
0
0
0
% P
% Gln:
0
0
13
13
0
0
0
0
0
0
0
0
13
0
13
% Q
% Arg:
0
0
0
63
13
0
0
13
0
0
25
38
0
38
0
% R
% Ser:
0
0
0
13
25
13
25
50
13
0
63
13
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
13
0
0
0
50
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _