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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PYGO1
All Species:
21.52
Human Site:
S196
Identified Species:
43.03
UniProt:
Q9Y3Y4
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y3Y4
NP_056432.1
419
45116
S196
P
Q
N
A
S
Q
V
S
N
P
D
L
A
S
N
Chimpanzee
Pan troglodytes
XP_523199
423
45720
S200
P
Q
N
A
S
Q
V
S
N
P
D
L
A
S
N
Rhesus Macaque
Macaca mulatta
XP_001090005
419
45094
S196
P
Q
N
A
S
Q
V
S
N
P
D
L
A
S
N
Dog
Lupus familis
XP_544693
462
49934
S239
P
Q
N
A
N
Q
V
S
N
P
D
L
A
S
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9D0P5
417
45071
S196
P
Q
N
V
G
Q
V
S
N
P
D
L
A
S
N
Rat
Rattus norvegicus
XP_001053933
417
45129
S196
P
Q
N
V
G
Q
V
S
N
P
D
L
A
S
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514326
407
43303
A184
P
Q
S
A
N
Q
M
A
N
P
D
M
V
S
H
Chicken
Gallus gallus
NP_001019862
418
44852
H195
G
H
S
G
Q
I
P
H
P
D
V
P
S
N
F
Frog
Xenopus laevis
NP_001082328
389
41400
G170
M
M
Q
G
P
V
G
G
F
G
P
M
M
S
P
Zebra Danio
Brachydanio rerio
NP_001107109
337
37389
Q118
T
Q
P
Q
Y
F
S
Q
N
P
T
G
F
S
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_394285
396
41911
G176
P
P
N
S
P
L
N
G
P
S
M
N
S
V
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791313
224
24117
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.8
98.5
86.1
N.A.
87.3
86.8
N.A.
74.2
69.9
35
42.7
N.A.
N.A.
22.2
N.A.
22.9
Protein Similarity:
100
95.7
99.2
88.9
N.A.
90.2
90.6
N.A.
83.7
81.6
47.2
56
N.A.
N.A.
39.3
N.A.
32.7
P-Site Identity:
100
100
100
93.3
N.A.
86.6
86.6
N.A.
53.3
0
6.6
26.6
N.A.
N.A.
20
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
86.6
86.6
N.A.
93.3
20
13.3
26.6
N.A.
N.A.
33.3
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
42
0
0
0
9
0
0
0
0
50
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
9
59
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
9
0
0
9
0
0
0
9
0
9
% F
% Gly:
9
0
0
17
17
0
9
17
0
9
0
9
0
0
0
% G
% His:
0
9
0
0
0
0
0
9
0
0
0
0
0
0
9
% H
% Ile:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
9
0
0
0
0
0
50
0
0
0
% L
% Met:
9
9
0
0
0
0
9
0
0
0
9
17
9
0
0
% M
% Asn:
0
0
59
0
17
0
9
0
67
0
0
9
0
9
59
% N
% Pro:
67
9
9
0
17
0
9
0
17
67
9
9
0
0
9
% P
% Gln:
0
67
9
9
9
59
0
9
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% R
% Ser:
0
0
17
9
25
0
9
50
0
9
0
0
17
75
0
% S
% Thr:
9
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% T
% Val:
0
0
0
17
0
9
50
0
0
0
9
0
9
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _