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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PYGO1
All Species:
24.85
Human Site:
S322
Identified Species:
49.7
UniProt:
Q9Y3Y4
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y3Y4
NP_056432.1
419
45116
S322
D
A
C
T
T
E
K
S
N
K
S
S
L
H
P
Chimpanzee
Pan troglodytes
XP_523199
423
45720
S326
D
A
C
T
T
E
K
S
N
K
S
S
L
H
P
Rhesus Macaque
Macaca mulatta
XP_001090005
419
45094
S322
D
A
C
T
T
E
K
S
N
K
S
S
L
H
P
Dog
Lupus familis
XP_544693
462
49934
S365
D
T
C
T
T
E
K
S
N
K
S
S
L
H
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9D0P5
417
45071
S320
D
L
C
T
P
D
K
S
R
K
F
S
L
L
P
Rat
Rattus norvegicus
XP_001053933
417
45129
S320
D
L
C
T
T
D
K
S
R
K
F
S
L
H
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514326
407
43303
N310
A
G
G
S
S
E
K
N
S
K
S
T
L
P
L
Chicken
Gallus gallus
NP_001019862
418
44852
S321
E
G
C
N
S
E
K
S
S
K
T
P
L
H
P
Frog
Xenopus laevis
NP_001082328
389
41400
P293
P
E
V
N
N
I
P
P
P
S
K
P
T
G
N
Zebra Danio
Brachydanio rerio
NP_001107109
337
37389
S241
H
S
N
N
E
K
K
S
P
D
Y
R
R
S
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_394285
396
41911
P299
Q
G
P
P
G
M
G
P
K
P
M
P
V
S
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791313
224
24117
P128
P
P
G
G
G
P
Y
P
N
N
M
A
N
S
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.8
98.5
86.1
N.A.
87.3
86.8
N.A.
74.2
69.9
35
42.7
N.A.
N.A.
22.2
N.A.
22.9
Protein Similarity:
100
95.7
99.2
88.9
N.A.
90.2
90.6
N.A.
83.7
81.6
47.2
56
N.A.
N.A.
39.3
N.A.
32.7
P-Site Identity:
100
100
100
93.3
N.A.
60
73.3
N.A.
33.3
53.3
0
13.3
N.A.
N.A.
0
N.A.
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
66.6
80
N.A.
66.6
80
0
26.6
N.A.
N.A.
6.6
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
25
0
0
0
0
0
0
0
0
0
9
0
0
17
% A
% Cys:
0
0
59
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
50
0
0
0
0
17
0
0
0
9
0
0
0
0
0
% D
% Glu:
9
9
0
0
9
50
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
17
0
0
0
0
% F
% Gly:
0
25
17
9
17
0
9
0
0
0
0
0
0
9
0
% G
% His:
9
0
0
0
0
0
0
0
0
0
0
0
0
50
9
% H
% Ile:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
9
75
0
9
67
9
0
0
0
0
% K
% Leu:
0
17
0
0
0
0
0
0
0
0
0
0
67
9
9
% L
% Met:
0
0
0
0
0
9
0
0
0
0
17
0
0
0
0
% M
% Asn:
0
0
9
25
9
0
0
9
42
9
0
0
9
0
9
% N
% Pro:
17
9
9
9
9
9
9
25
17
9
0
25
0
9
59
% P
% Gln:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
17
0
0
9
9
0
0
% R
% Ser:
0
9
0
9
17
0
0
67
17
9
42
50
0
25
0
% S
% Thr:
0
9
0
50
42
0
0
0
0
0
9
9
9
0
0
% T
% Val:
0
0
9
0
0
0
0
0
0
0
0
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
9
0
0
0
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _