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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PYGO1
All Species:
23.64
Human Site:
T249
Identified Species:
47.27
UniProt:
Q9Y3Y4
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y3Y4
NP_056432.1
419
45116
T249
T
Q
G
A
T
K
N
T
N
Q
N
S
S
A
H
Chimpanzee
Pan troglodytes
XP_523199
423
45720
T253
T
Q
G
A
T
K
I
T
N
Q
N
S
S
A
H
Rhesus Macaque
Macaca mulatta
XP_001090005
419
45094
T249
P
Q
G
A
T
K
N
T
N
Q
N
S
S
A
H
Dog
Lupus familis
XP_544693
462
49934
T292
S
Q
G
A
T
K
N
T
N
Q
N
S
S
T
H
Cat
Felis silvestris
Mouse
Mus musculus
Q9D0P5
417
45071
P249
T
Q
G
A
T
K
T
P
N
Q
N
S
S
T
H
Rat
Rattus norvegicus
XP_001053933
417
45129
T249
T
Q
G
A
A
K
T
T
N
Q
N
S
S
T
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514326
407
43303
T237
H
Q
G
Q
S
K
N
T
A
Q
N
S
S
A
H
Chicken
Gallus gallus
NP_001019862
418
44852
S248
S
Q
A
A
S
K
A
S
S
Q
N
T
A
A
L
Frog
Xenopus laevis
NP_001082328
389
41400
P223
P
V
P
R
A
S
L
P
P
N
T
S
P
F
A
Zebra Danio
Brachydanio rerio
NP_001107109
337
37389
G171
N
L
N
Q
R
S
P
G
F
N
P
D
A
N
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_394285
396
41911
P229
N
N
L
N
M
S
G
P
N
Q
I
N
N
M
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791313
224
24117
N58
G
S
G
S
A
G
G
N
L
A
P
P
P
T
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.8
98.5
86.1
N.A.
87.3
86.8
N.A.
74.2
69.9
35
42.7
N.A.
N.A.
22.2
N.A.
22.9
Protein Similarity:
100
95.7
99.2
88.9
N.A.
90.2
90.6
N.A.
83.7
81.6
47.2
56
N.A.
N.A.
39.3
N.A.
32.7
P-Site Identity:
100
93.3
93.3
86.6
N.A.
80
80
N.A.
73.3
40
6.6
0
N.A.
N.A.
13.3
N.A.
6.6
P-Site Similarity:
100
93.3
93.3
93.3
N.A.
80
80
N.A.
80
80
6.6
6.6
N.A.
N.A.
33.3
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
59
25
0
9
0
9
9
0
0
17
42
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
9
0
0
0
0
9
0
% F
% Gly:
9
0
67
0
0
9
17
9
0
0
0
0
0
0
0
% G
% His:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
59
% H
% Ile:
0
0
0
0
0
0
9
0
0
0
9
0
0
0
0
% I
% Lys:
0
0
0
0
0
67
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
9
9
0
0
0
9
0
9
0
0
0
0
0
9
% L
% Met:
0
0
0
0
9
0
0
0
0
0
0
0
0
9
0
% M
% Asn:
17
9
9
9
0
0
34
9
59
17
67
9
9
9
9
% N
% Pro:
17
0
9
0
0
0
9
25
9
0
17
9
17
0
9
% P
% Gln:
0
67
0
17
0
0
0
0
0
75
0
0
0
0
0
% Q
% Arg:
0
0
0
9
9
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
17
9
0
9
17
25
0
9
9
0
0
67
59
0
0
% S
% Thr:
34
0
0
0
42
0
17
50
0
0
9
9
0
34
9
% T
% Val:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _