KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SAMHD1
All Species:
5.45
Human Site:
T463
Identified Species:
10
UniProt:
Q9Y3Z3
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y3Z3
NP_056289.2
626
72201
T463
Y
V
G
E
T
Q
P
T
G
Q
I
K
I
K
R
Chimpanzee
Pan troglodytes
XP_514624
382
43769
T232
A
R
P
E
V
K
W
T
H
E
Q
G
S
V
M
Rhesus Macaque
Macaca mulatta
XP_001097562
728
83194
T565
Y
V
G
E
T
Q
P
T
E
Q
V
K
I
K
K
Dog
Lupus familis
XP_542986
665
76981
K501
Y
V
G
E
T
K
P
K
G
K
I
R
I
E
R
Cat
Felis silvestris
Mouse
Mus musculus
Q60710
627
72632
K475
Y
L
G
E
T
Q
P
K
R
E
K
I
R
K
E
Rat
Rattus norvegicus
XP_230789
677
77635
K525
Y
L
G
E
T
Q
P
K
R
E
K
I
K
K
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZJL9
614
70202
E454
F
L
G
E
T
Q
P
E
K
V
N
E
I
P
K
Frog
Xenopus laevis
Q6INN8
632
72730
H468
Y
I
G
Q
T
H
P
H
S
N
S
R
I
E
P
Zebra Danio
Brachydanio rerio
Q502K2
622
71649
E443
C
V
G
Q
T
T
S
E
T
N
V
D
V
S
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09374
587
66474
N416
K
L
G
Y
F
E
M
N
P
E
N
A
T
Q
L
Sea Urchin
Strong. purpuratus
XP_784786
594
68895
F444
Y
V
G
E
S
P
V
F
K
K
L
D
P
E
L
Poplar Tree
Populus trichocarpa
XP_002312899
477
54770
E327
A
P
N
Q
E
L
R
E
S
R
N
L
I
R
R
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_568580
473
54655
A323
I
A
P
D
P
E
L
A
E
A
K
E
L
I
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
58.9
79.5
73.5
N.A.
73.3
65.8
N.A.
N.A.
60
61.8
60.8
N.A.
N.A.
N.A.
22.5
46.8
Protein Similarity:
100
60.2
82.4
83.6
N.A.
83.2
76.2
N.A.
N.A.
74.9
75.3
74.1
N.A.
N.A.
N.A.
40.8
64.2
P-Site Identity:
100
13.3
80
66.6
N.A.
46.6
46.6
N.A.
N.A.
40
33.3
20
N.A.
N.A.
N.A.
6.6
26.6
P-Site Similarity:
100
26.6
93.3
93.3
N.A.
60
60
N.A.
N.A.
66.6
60
46.6
N.A.
N.A.
N.A.
33.3
53.3
Percent
Protein Identity:
28.2
N.A.
N.A.
30.5
N.A.
N.A.
Protein Similarity:
45
N.A.
N.A.
47.2
N.A.
N.A.
P-Site Identity:
13.3
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
33.3
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
8
0
0
0
0
0
8
0
8
0
8
0
0
8
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
0
0
0
0
0
0
16
0
0
0
% D
% Glu:
0
0
0
62
8
16
0
24
16
31
0
16
0
24
8
% E
% Phe:
8
0
0
0
8
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
77
0
0
0
0
0
16
0
0
8
0
0
0
% G
% His:
0
0
0
0
0
8
0
8
8
0
0
0
0
0
0
% H
% Ile:
8
8
0
0
0
0
0
0
0
0
16
16
47
8
0
% I
% Lys:
8
0
0
0
0
16
0
24
16
16
24
16
8
31
16
% K
% Leu:
0
31
0
0
0
8
8
0
0
0
8
8
8
0
24
% L
% Met:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
8
% M
% Asn:
0
0
8
0
0
0
0
8
0
16
24
0
0
0
0
% N
% Pro:
0
8
16
0
8
8
54
0
8
0
0
0
8
8
8
% P
% Gln:
0
0
0
24
0
39
0
0
0
16
8
0
0
8
8
% Q
% Arg:
0
8
0
0
0
0
8
0
16
8
0
16
8
8
24
% R
% Ser:
0
0
0
0
8
0
8
0
16
0
8
0
8
8
0
% S
% Thr:
0
0
0
0
62
8
0
24
8
0
0
0
8
0
0
% T
% Val:
0
39
0
0
8
0
8
0
0
8
16
0
8
8
0
% V
% Trp:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
54
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _