KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SAMHD1
All Species:
5.76
Human Site:
Y563
Identified Species:
10.56
UniProt:
Q9Y3Z3
Number Species:
12
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y3Z3
NP_056289.2
626
72201
Y563
K
V
D
R
K
S
L
Y
A
A
R
Q
Y
F
V
Chimpanzee
Pan troglodytes
XP_514624
382
43769
H322
Y
F
A
R
D
C
H
H
L
G
I
Q
N
N
F
Rhesus Macaque
Macaca mulatta
XP_001097562
728
83194
Y665
K
M
D
R
K
S
L
Y
A
A
K
Q
H
F
V
Dog
Lupus familis
XP_542986
665
76981
F602
K
T
D
A
D
T
L
F
A
V
K
Q
H
F
V
Cat
Felis silvestris
Mouse
Mus musculus
Q60710
627
72632
C565
E
Q
L
I
R
V
Y
C
K
K
K
D
G
K
S
Rat
Rattus norvegicus
XP_230789
677
77635
Y615
E
Q
L
I
R
V
Y
Y
K
K
K
D
K
K
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZJL9
614
70202
C546
E
Q
V
I
R
V
Y
C
K
R
Q
D
P
I
I
Frog
Xenopus laevis
Q6INN8
632
72730
E569
K
T
D
E
K
S
L
E
T
A
K
R
Y
F
I
Zebra Danio
Brachydanio rerio
Q502K2
622
71649
E542
K
T
D
D
K
S
L
E
A
A
K
K
Y
F
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09374
587
66474
I525
R
M
A
T
K
W
E
I
F
V
M
G
D
R
S
Sea Urchin
Strong. purpuratus
XP_784786
594
68895
D534
Y
I
R
L
Y
C
K
D
C
G
A
E
N
V
K
Poplar Tree
Populus trichocarpa
XP_002312899
477
54770
I417
E
S
E
E
K
F
S
I
P
D
D
R
I
S
H
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_568580
473
54655
P413
S
A
E
K
F
V
I
P
E
D
R
V
S
H
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
58.9
79.5
73.5
N.A.
73.3
65.8
N.A.
N.A.
60
61.8
60.8
N.A.
N.A.
N.A.
22.5
46.8
Protein Similarity:
100
60.2
82.4
83.6
N.A.
83.2
76.2
N.A.
N.A.
74.9
75.3
74.1
N.A.
N.A.
N.A.
40.8
64.2
P-Site Identity:
100
13.3
80
46.6
N.A.
0
6.6
N.A.
N.A.
0
53.3
66.6
N.A.
N.A.
N.A.
6.6
0
P-Site Similarity:
100
20
100
73.3
N.A.
20
26.6
N.A.
N.A.
26.6
73.3
80
N.A.
N.A.
N.A.
20
13.3
Percent
Protein Identity:
28.2
N.A.
N.A.
30.5
N.A.
N.A.
Protein Similarity:
45
N.A.
N.A.
47.2
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
16
8
0
0
0
0
31
31
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
16
0
16
8
0
0
0
0
0
0
% C
% Asp:
0
0
39
8
16
0
0
8
0
16
8
24
8
0
0
% D
% Glu:
31
0
16
16
0
0
8
16
8
0
0
8
0
0
0
% E
% Phe:
0
8
0
0
8
8
0
8
8
0
0
0
0
39
8
% F
% Gly:
0
0
0
0
0
0
0
0
0
16
0
8
8
0
0
% G
% His:
0
0
0
0
0
0
8
8
0
0
0
0
16
8
8
% H
% Ile:
0
8
0
24
0
0
8
16
0
0
8
0
8
8
16
% I
% Lys:
39
0
0
8
47
0
8
0
24
16
47
8
8
16
8
% K
% Leu:
0
0
16
8
0
0
39
0
8
0
0
0
0
0
8
% L
% Met:
0
16
0
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
16
8
0
% N
% Pro:
0
0
0
0
0
0
0
8
8
0
0
0
8
0
0
% P
% Gln:
0
24
0
0
0
0
0
0
0
0
8
31
0
0
0
% Q
% Arg:
8
0
8
24
24
0
0
0
0
8
16
16
0
8
0
% R
% Ser:
8
8
0
0
0
31
8
0
0
0
0
0
8
8
24
% S
% Thr:
0
24
0
8
0
8
0
0
8
0
0
0
0
0
0
% T
% Val:
0
8
8
0
0
31
0
0
0
16
0
8
0
8
31
% V
% Trp:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% W
% Tyr:
16
0
0
0
8
0
24
24
0
0
0
0
24
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _