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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBX22
All Species:
6.67
Human Site:
S421
Identified Species:
14.67
UniProt:
Q9Y458
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y458
NP_001103348.1
520
57910
S421
S
S
L
G
V
T
N
S
K
S
G
S
S
E
D
Chimpanzee
Pan troglodytes
XP_529056
490
54602
K392
S
L
G
V
T
N
S
K
S
G
S
S
E
D
S
Rhesus Macaque
Macaca mulatta
XP_001102902
519
57880
S420
S
S
L
G
V
T
N
S
K
S
G
S
S
E
D
Dog
Lupus familis
XP_540262
602
65715
S471
A
Y
G
G
Q
L
G
S
F
P
T
S
Q
F
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8K402
517
58479
P418
S
S
R
G
I
I
N
P
N
S
G
L
H
E
D
Rat
Rattus norvegicus
Q5I2P1
517
57726
S407
W
P
S
M
P
S
Y
S
S
C
T
V
T
T
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509854
596
63747
N456
V
A
S
G
A
T
V
N
M
S
M
A
G
N
D
Chicken
Gallus gallus
Q8UW76
440
48669
W342
D
N
L
S
L
S
S
W
V
S
S
S
T
S
F
Frog
Xenopus laevis
Q8AXW8
441
48933
W343
D
N
L
S
L
S
S
W
V
S
S
T
S
G
F
Zebra Danio
Brachydanio rerio
Q9I9K7
446
49284
W348
D
N
L
S
L
S
S
W
V
T
T
T
S
G
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P90971
346
39417
Q248
F
M
A
V
T
A
Y
Q
N
Q
L
I
T
K
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.5
95.5
42.1
N.A.
72.1
31.1
N.A.
41.6
32.6
33
33.2
N.A.
N.A.
N.A.
30.3
N.A.
Protein Similarity:
100
93.6
97.3
56.9
N.A.
80.5
46.5
N.A.
56.3
47.3
47.1
46.9
N.A.
N.A.
N.A.
44.2
N.A.
P-Site Identity:
100
13.3
100
20
N.A.
53.3
6.6
N.A.
26.6
20
20
13.3
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
26.6
100
26.6
N.A.
60
20
N.A.
46.6
53.3
53.3
53.3
N.A.
N.A.
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
10
0
10
10
0
0
0
0
0
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% C
% Asp:
28
0
0
0
0
0
0
0
0
0
0
0
0
10
37
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
10
28
0
% E
% Phe:
10
0
0
0
0
0
0
0
10
0
0
0
0
10
28
% F
% Gly:
0
0
19
46
0
0
10
0
0
10
28
0
10
19
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% H
% Ile:
0
0
0
0
10
10
0
0
0
0
0
10
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
10
19
0
0
0
0
10
0
% K
% Leu:
0
10
46
0
28
10
0
0
0
0
10
10
0
0
10
% L
% Met:
0
10
0
10
0
0
0
0
10
0
10
0
0
0
0
% M
% Asn:
0
28
0
0
0
10
28
10
19
0
0
0
0
10
0
% N
% Pro:
0
10
0
0
10
0
0
10
0
10
0
0
0
0
0
% P
% Gln:
0
0
0
0
10
0
0
10
0
10
0
0
10
0
10
% Q
% Arg:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
37
28
19
28
0
37
37
37
19
55
28
46
37
10
10
% S
% Thr:
0
0
0
0
19
28
0
0
0
10
28
19
28
10
0
% T
% Val:
10
0
0
19
19
0
10
0
28
0
0
10
0
0
10
% V
% Trp:
10
0
0
0
0
0
0
28
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
0
19
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _