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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NR2E1 All Species: 15.45
Human Site: S307 Identified Species: 30.91
UniProt: Q9Y466 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.36
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y466 NP_003260.1 385 42589 S307 H S G S E L R S F R N A A A I
Chimpanzee Pan troglodytes XP_001175025 402 43746 K329 K P E T R G L K D P E H V E A
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_532253 385 42541 S307 H S G S E L R S F R N A A A I
Cat Felis silvestris
Mouse Mus musculus Q64104 385 42601 S307 H S G S E L R S F R N A A A I
Rat Rattus norvegicus O09018 414 45583 S329 T S D A C G L S D V A H V E S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q91379 385 42465 S307 H S G S E L R S F R N A A A I
Frog Xenopus laevis P70052 386 42956 R307 T H S G S E L R N F R N A A A
Zebra Danio Brachydanio rerio Q06725 411 45463 S326 T S D A C G L S D A A H I E S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P18102 452 50531 L352 S A S S T E D L A N S S I L T
Honey Bee Apis mellifera XP_001121187 418 45540 R330 S E P L P S S R S S N G S T S
Nematode Worm Caenorhab. elegans Q9XVV3 416 46752 A319 P T S L F P M A N F N L N F L
Sea Urchin Strong. purpuratus XP_794533 367 40609 K290 K T D I S G I K E T S S V V T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 44.5 N.A. 99.7 N.A. 98.9 27.5 N.A. N.A. 97.1 91.1 26.2 N.A. 40.4 42.3 28.8 56.3
Protein Similarity: 100 60.7 N.A. 99.7 N.A. 99.2 46.1 N.A. N.A. 98.1 94.5 45 N.A. 56.6 55.7 43.9 70.9
P-Site Identity: 100 0 N.A. 100 N.A. 100 13.3 N.A. N.A. 100 13.3 13.3 N.A. 6.6 6.6 6.6 0
P-Site Similarity: 100 6.6 N.A. 100 N.A. 100 20 N.A. N.A. 100 13.3 20 N.A. 26.6 13.3 26.6 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 17 0 0 0 9 9 9 17 34 42 42 17 % A
% Cys: 0 0 0 0 17 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 25 0 0 0 9 0 25 0 0 0 0 0 0 % D
% Glu: 0 9 9 0 34 17 0 0 9 0 9 0 0 25 0 % E
% Phe: 0 0 0 0 9 0 0 0 34 17 0 0 0 9 0 % F
% Gly: 0 0 34 9 0 34 0 0 0 0 0 9 0 0 0 % G
% His: 34 9 0 0 0 0 0 0 0 0 0 25 0 0 0 % H
% Ile: 0 0 0 9 0 0 9 0 0 0 0 0 17 0 34 % I
% Lys: 17 0 0 0 0 0 0 17 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 17 0 34 34 9 0 0 0 9 0 9 9 % L
% Met: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 17 9 50 9 9 0 0 % N
% Pro: 9 9 9 0 9 9 0 0 0 9 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 9 0 34 17 0 34 9 0 0 0 0 % R
% Ser: 17 50 25 42 17 9 9 50 9 9 17 17 9 0 25 % S
% Thr: 25 17 0 9 9 0 0 0 0 9 0 0 0 9 17 % T
% Val: 0 0 0 0 0 0 0 0 0 9 0 0 25 9 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _