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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NR2E1
All Species:
28.18
Human Site:
T335
Identified Species:
56.36
UniProt:
Q9Y466
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y466
NP_003260.1
385
42589
T335
Y
I
H
T
R
Y
P
T
Q
P
C
R
F
G
K
Chimpanzee
Pan troglodytes
XP_001175025
402
43746
S355
H
S
K
A
H
H
P
S
Q
P
V
R
F
G
K
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_532253
385
42541
T335
Y
I
H
T
R
Y
P
T
Q
P
C
R
F
G
K
Cat
Felis silvestris
Mouse
Mus musculus
Q64104
385
42601
T335
Y
I
H
T
R
Y
P
T
Q
P
C
R
F
G
K
Rat
Rattus norvegicus
O09018
414
45583
N355
Y
V
R
S
Q
Y
P
N
Q
P
T
R
F
G
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q91379
385
42465
T335
Y
I
H
T
R
Y
P
T
Q
P
C
R
F
G
K
Frog
Xenopus laevis
P70052
386
42956
T336
Y
I
H
T
R
Y
P
T
Q
P
C
R
F
G
K
Zebra Danio
Brachydanio rerio
Q06725
411
45463
N352
Y
V
R
S
Q
Y
P
N
Q
P
S
R
F
G
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P18102
452
50531
S402
Y
I
Q
R
T
H
P
S
Q
P
M
R
F
Q
T
Honey Bee
Apis mellifera
XP_001121187
418
45540
L365
Q
L
A
L
G
Q
R
L
S
G
A
S
F
G
A
Nematode Worm
Caenorhab. elegans
Q9XVV3
416
46752
T358
Q
F
D
E
N
S
S
T
D
D
R
S
V
G
E
Sea Urchin
Strong. purpuratus
XP_794533
367
40609
T316
Y
I
T
V
R
H
Q
T
Q
P
Y
R
F
G
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
44.5
N.A.
99.7
N.A.
98.9
27.5
N.A.
N.A.
97.1
91.1
26.2
N.A.
40.4
42.3
28.8
56.3
Protein Similarity:
100
60.7
N.A.
99.7
N.A.
99.2
46.1
N.A.
N.A.
98.1
94.5
45
N.A.
56.6
55.7
43.9
70.9
P-Site Identity:
100
46.6
N.A.
100
N.A.
100
60
N.A.
N.A.
100
100
60
N.A.
46.6
13.3
13.3
66.6
P-Site Similarity:
100
66.6
N.A.
100
N.A.
100
80
N.A.
N.A.
100
100
80
N.A.
60
20
20
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
9
0
0
0
0
0
0
9
0
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
42
0
0
0
0
% C
% Asp:
0
0
9
0
0
0
0
0
9
9
0
0
0
0
0
% D
% Glu:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
9
% E
% Phe:
0
9
0
0
0
0
0
0
0
0
0
0
92
0
0
% F
% Gly:
0
0
0
0
9
0
0
0
0
9
0
0
0
92
0
% G
% His:
9
0
42
0
9
25
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
59
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
75
% K
% Leu:
0
9
0
9
0
0
0
9
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% M
% Asn:
0
0
0
0
9
0
0
17
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
75
0
0
84
0
0
0
0
0
% P
% Gln:
17
0
9
0
17
9
9
0
84
0
0
0
0
9
0
% Q
% Arg:
0
0
17
9
50
0
9
0
0
0
9
84
0
0
0
% R
% Ser:
0
9
0
17
0
9
9
17
9
0
9
17
0
0
0
% S
% Thr:
0
0
9
42
9
0
0
59
0
0
9
0
0
0
9
% T
% Val:
0
17
0
9
0
0
0
0
0
0
9
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
75
0
0
0
0
59
0
0
0
0
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _