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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NR2E1
All Species:
19.39
Human Site:
Y176
Identified Species:
38.79
UniProt:
Q9Y466
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y466
NP_003260.1
385
42589
Y176
E
V
N
G
T
P
M
Y
L
Y
E
V
A
T
E
Chimpanzee
Pan troglodytes
XP_001175025
402
43746
S203
F
P
S
S
P
Y
S
S
S
S
P
C
G
L
D
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_532253
385
42541
Y176
E
V
N
G
T
P
M
Y
L
Y
E
V
A
T
E
Cat
Felis silvestris
Mouse
Mus musculus
Q64104
385
42601
Y176
E
V
N
G
T
P
M
Y
L
Y
E
V
A
T
E
Rat
Rattus norvegicus
O09018
414
45583
P203
F
G
S
Q
C
M
Q
P
N
N
I
M
G
I
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q91379
385
42465
Y176
E
V
N
G
T
P
M
Y
L
Y
E
V
A
T
E
Frog
Xenopus laevis
P70052
386
42956
Y176
E
V
N
G
A
P
L
Y
L
Y
E
F
A
T
E
Zebra Danio
Brachydanio rerio
Q06725
411
45463
P200
Y
G
S
Q
C
M
Q
P
N
N
I
M
G
I
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P18102
452
50531
T223
A
T
R
A
L
P
P
T
P
P
L
M
A
A
E
Honey Bee
Apis mellifera
XP_001121187
418
45540
I208
G
L
P
T
L
P
L
I
P
A
A
I
T
A
E
Nematode Worm
Caenorhab. elegans
Q9XVV3
416
46752
V184
Q
N
W
A
A
L
L
V
L
H
A
T
E
T
R
Sea Urchin
Strong. purpuratus
XP_794533
367
40609
M164
P
H
E
P
V
T
M
M
P
P
V
G
S
V
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
44.5
N.A.
99.7
N.A.
98.9
27.5
N.A.
N.A.
97.1
91.1
26.2
N.A.
40.4
42.3
28.8
56.3
Protein Similarity:
100
60.7
N.A.
99.7
N.A.
99.2
46.1
N.A.
N.A.
98.1
94.5
45
N.A.
56.6
55.7
43.9
70.9
P-Site Identity:
100
0
N.A.
100
N.A.
100
6.6
N.A.
N.A.
100
80
6.6
N.A.
20
13.3
13.3
6.6
P-Site Similarity:
100
13.3
N.A.
100
N.A.
100
20
N.A.
N.A.
100
86.6
20
N.A.
26.6
33.3
33.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
17
17
0
0
0
0
9
17
0
50
17
0
% A
% Cys:
0
0
0
0
17
0
0
0
0
0
0
9
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
17
% D
% Glu:
42
0
9
0
0
0
0
0
0
0
42
0
9
0
75
% E
% Phe:
17
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% F
% Gly:
9
17
0
42
0
0
0
0
0
0
0
9
25
0
0
% G
% His:
0
9
0
0
0
0
0
0
0
9
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
9
0
0
17
9
0
17
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
9
0
0
17
9
25
0
50
0
9
0
0
9
0
% L
% Met:
0
0
0
0
0
17
42
9
0
0
0
25
0
0
0
% M
% Asn:
0
9
42
0
0
0
0
0
17
17
0
0
0
0
0
% N
% Pro:
9
9
9
9
9
59
9
17
25
17
9
0
0
0
0
% P
% Gln:
9
0
0
17
0
0
17
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
9
% R
% Ser:
0
0
25
9
0
0
9
9
9
9
0
0
9
0
0
% S
% Thr:
0
9
0
9
34
9
0
9
0
0
0
9
9
50
0
% T
% Val:
0
42
0
0
9
0
0
9
0
0
9
34
0
9
0
% V
% Trp:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
0
9
0
42
0
42
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _