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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NR2E1
All Species:
23.9
Human Site:
Y380
Identified Species:
47.8
UniProt:
Q9Y466
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y466
NP_003260.1
385
42589
Y380
T
R
L
L
S
D
M
Y
K
S
S
D
I
_
_
Chimpanzee
Pan troglodytes
XP_001175025
402
43746
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_532253
385
42541
Y380
T
R
L
L
S
D
M
Y
K
S
S
D
I
_
_
Cat
Felis silvestris
Mouse
Mus musculus
Q64104
385
42601
Y380
T
R
L
L
S
D
M
Y
K
S
S
D
I
_
_
Rat
Rattus norvegicus
O09018
414
45583
L400
E
T
L
I
R
D
M
L
L
S
G
S
S
F
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q91379
385
42465
Y380
T
R
L
L
S
D
M
Y
K
S
S
D
I
_
_
Frog
Xenopus laevis
P70052
386
42956
Y381
T
R
V
L
S
D
M
Y
K
S
S
D
I
_
_
Zebra Danio
Brachydanio rerio
Q06725
411
45463
L397
E
T
L
I
R
D
M
L
L
S
G
S
S
F
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P18102
452
50531
Y447
V
R
L
I
S
D
M
Y
S
Q
R
K
I
_
_
Honey Bee
Apis mellifera
XP_001121187
418
45540
C412
I
P
I
E
R
I
I
C
D
M
Y
K
A
A
_
Nematode Worm
Caenorhab. elegans
Q9XVV3
416
46752
E409
L
L
S
I
Q
E
E
E
S
V
N
V
E
E
V
Sea Urchin
Strong. purpuratus
XP_794533
367
40609
Y361
H
T
L
L
T
D
L
Y
K
K
N
E
H
F
_
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
44.5
N.A.
99.7
N.A.
98.9
27.5
N.A.
N.A.
97.1
91.1
26.2
N.A.
40.4
42.3
28.8
56.3
Protein Similarity:
100
60.7
N.A.
99.7
N.A.
99.2
46.1
N.A.
N.A.
98.1
94.5
45
N.A.
56.6
55.7
43.9
70.9
P-Site Identity:
100
0
N.A.
100
N.A.
100
26.6
N.A.
N.A.
100
92.3
26.6
N.A.
53.8
0
0
35.7
P-Site Similarity:
100
0
N.A.
100
N.A.
100
33.3
N.A.
N.A.
100
100
33.3
N.A.
61.5
14.2
20
64.2
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
9
9
0
% A
% Cys:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
75
0
0
9
0
0
42
0
0
0
% D
% Glu:
17
0
0
9
0
9
9
9
0
0
0
9
9
9
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
25
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
17
0
0
0
0
% G
% His:
9
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% H
% Ile:
9
0
9
34
0
9
9
0
0
0
0
0
50
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
50
9
0
17
0
0
0
% K
% Leu:
9
9
67
50
0
0
9
17
17
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
67
0
0
9
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
17
0
0
0
17
% N
% Pro:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
9
0
0
0
0
9
0
0
0
0
0
% Q
% Arg:
0
50
0
0
25
0
0
0
0
0
9
0
0
0
0
% R
% Ser:
0
0
9
0
50
0
0
0
17
59
42
17
17
0
0
% S
% Thr:
42
25
0
0
9
0
0
0
0
0
0
0
0
0
0
% T
% Val:
9
0
9
0
0
0
0
0
0
9
0
9
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
59
0
0
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
50
67
% _