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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKAB1
All Species:
26.97
Human Site:
S108
Identified Species:
42.38
UniProt:
Q9Y478
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.43
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y478
NP_006244.2
270
30382
S108
S
K
L
P
L
T
R
S
H
N
N
F
V
A
I
Chimpanzee
Pan troglodytes
XP_513749
272
30341
K107
S
T
K
I
P
L
I
K
S
H
N
D
F
V
A
Rhesus Macaque
Macaca mulatta
XP_001093423
272
30312
K107
S
T
K
I
P
L
I
K
S
H
N
D
F
V
A
Dog
Lupus familis
XP_543421
270
30281
S108
S
K
L
P
L
T
R
S
H
N
N
F
V
A
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9R078
270
30290
S108
S
K
L
P
L
T
R
S
Q
N
N
F
V
A
I
Rat
Rattus norvegicus
P80386
270
30376
S108
S
K
L
P
L
T
R
S
Q
N
N
F
V
A
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514296
285
32181
K120
S
A
K
I
P
L
I
K
S
H
N
D
F
V
A
Chicken
Gallus gallus
NP_001035001
273
30440
S111
S
K
I
P
L
T
R
S
H
N
N
F
V
A
I
Frog
Xenopus laevis
NP_001085572
266
29829
S104
A
K
I
P
L
I
R
S
R
N
N
F
F
A
I
Zebra Danio
Brachydanio rerio
NP_001002632
268
30343
R105
T
N
K
I
P
L
I
R
S
Q
N
N
F
V
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610460
341
36399
S185
K
P
M
A
M
V
R
S
H
Q
N
F
V
T
I
Honey Bee
Apis mellifera
XP_393160
283
31818
S127
K
T
L
P
M
V
K
S
H
G
D
F
V
T
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797535
279
30846
K112
N
T
K
I
P
M
I
K
S
Q
G
D
F
T
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SCY5
289
31974
R132
K
T
R
S
R
L
Q
R
S
G
K
D
F
T
I
Baker's Yeast
Sacchar. cerevisiae
P34164
415
46386
P194
R
K
M
I
G
L
I
P
D
S
D
N
N
G
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
70.5
70.9
98.5
N.A.
96.6
96.3
N.A.
63.8
91.2
80.3
81.1
N.A.
43.9
50.1
N.A.
49.4
Protein Similarity:
100
82.3
82.3
98.8
N.A.
97.7
98.5
N.A.
71.9
94.8
87.7
89.6
N.A.
54.8
66
N.A.
65.2
P-Site Identity:
100
13.3
13.3
100
N.A.
93.3
93.3
N.A.
13.3
93.3
66.6
6.6
N.A.
46.6
46.6
N.A.
0
P-Site Similarity:
100
20
20
100
N.A.
93.3
93.3
N.A.
20
100
80
13.3
N.A.
60
66.6
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
32.8
28.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.7
39.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
0
7
0
0
0
0
0
0
0
0
0
40
34
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
7
0
14
34
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
54
47
0
0
% F
% Gly:
0
0
0
0
7
0
0
0
0
14
7
0
0
7
0
% G
% His:
0
0
0
0
0
0
0
0
34
20
0
0
0
0
0
% H
% Ile:
0
0
14
40
0
7
40
0
0
0
0
0
0
0
60
% I
% Lys:
20
47
34
0
0
0
7
27
0
0
7
0
0
0
0
% K
% Leu:
0
0
34
0
40
40
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
14
0
14
7
0
0
0
0
0
0
0
0
0
% M
% Asn:
7
7
0
0
0
0
0
0
0
40
74
14
7
0
0
% N
% Pro:
0
7
0
47
34
0
0
7
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
7
0
14
20
0
0
0
0
0
% Q
% Arg:
7
0
7
0
7
0
47
14
7
0
0
0
0
0
0
% R
% Ser:
54
0
0
7
0
0
0
54
40
7
0
0
0
0
7
% S
% Thr:
7
34
0
0
0
34
0
0
0
0
0
0
0
27
0
% T
% Val:
0
0
0
0
0
14
0
0
0
0
0
0
47
27
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _