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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKAB1
All Species:
36.06
Human Site:
S144
Identified Species:
56.67
UniProt:
Q9Y478
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y478
NP_006244.2
270
30382
S144
P
S
E
P
I
V
T
S
Q
L
G
T
V
N
N
Chimpanzee
Pan troglodytes
XP_513749
272
30341
S144
P
S
E
P
V
V
T
S
Q
L
G
T
I
N
N
Rhesus Macaque
Macaca mulatta
XP_001093423
272
30312
S144
P
S
E
P
V
V
T
S
Q
L
G
T
I
N
N
Dog
Lupus familis
XP_543421
270
30281
S144
P
S
E
P
I
V
T
S
Q
L
G
T
V
N
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9R078
270
30290
S144
P
S
E
P
I
V
T
S
Q
L
G
T
V
N
N
Rat
Rattus norvegicus
P80386
270
30376
S144
P
S
E
P
I
V
T
S
Q
L
G
T
V
N
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514296
285
32181
S157
P
S
E
P
M
V
T
S
Q
L
G
T
I
N
N
Chicken
Gallus gallus
NP_001035001
273
30440
S147
P
S
E
P
V
V
T
S
Q
L
G
T
V
N
N
Frog
Xenopus laevis
NP_001085572
266
29829
S140
A
A
E
P
V
I
T
S
Q
L
G
T
V
N
N
Zebra Danio
Brachydanio rerio
NP_001002632
268
30343
N142
P
T
E
P
V
V
T
N
Q
L
G
T
V
N
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610460
341
36399
N221
P
K
L
K
S
V
E
N
A
E
G
Q
R
N
N
Honey Bee
Apis mellifera
XP_393160
283
31818
N163
P
D
I
K
I
V
D
N
G
M
G
S
K
N
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797535
279
30846
N149
P
R
Q
P
L
Q
S
N
T
F
G
T
V
N
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SCY5
289
31974
D169
P
E
L
P
L
A
R
D
D
A
G
N
T
F
N
Baker's Yeast
Sacchar. cerevisiae
P34164
415
46386
D234
D
F
L
P
T
A
T
D
Q
M
G
N
F
V
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
70.5
70.9
98.5
N.A.
96.6
96.3
N.A.
63.8
91.2
80.3
81.1
N.A.
43.9
50.1
N.A.
49.4
Protein Similarity:
100
82.3
82.3
98.8
N.A.
97.7
98.5
N.A.
71.9
94.8
87.7
89.6
N.A.
54.8
66
N.A.
65.2
P-Site Identity:
100
86.6
86.6
100
N.A.
100
100
N.A.
86.6
93.3
73.3
80
N.A.
33.3
40
N.A.
46.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
93.3
100
N.A.
40
60
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
32.8
28.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.7
39.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
33.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
0
0
0
14
0
0
7
7
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
7
0
0
0
0
7
14
7
0
0
0
0
0
0
% D
% Glu:
0
7
67
0
0
0
7
0
0
7
0
0
0
0
0
% E
% Phe:
0
7
0
0
0
0
0
0
0
7
0
0
7
7
0
% F
% Gly:
0
0
0
0
0
0
0
0
7
0
100
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
7
0
34
7
0
0
0
0
0
0
20
0
0
% I
% Lys:
0
7
0
14
0
0
0
0
0
0
0
0
7
0
0
% K
% Leu:
0
0
20
0
14
0
0
0
0
67
0
0
0
0
0
% L
% Met:
0
0
0
0
7
0
0
0
0
14
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
27
0
0
0
14
0
87
100
% N
% Pro:
87
0
0
87
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
7
0
0
7
0
0
74
0
0
7
0
0
0
% Q
% Arg:
0
7
0
0
0
0
7
0
0
0
0
0
7
0
0
% R
% Ser:
0
54
0
0
7
0
7
60
0
0
0
7
0
0
0
% S
% Thr:
0
7
0
0
7
0
74
0
7
0
0
74
7
0
0
% T
% Val:
0
0
0
0
34
74
0
0
0
0
0
0
54
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _