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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKAB1
All Species:
24.83
Human Site:
S6
Identified Species:
39.01
UniProt:
Q9Y478
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y478
NP_006244.2
270
30382
S6
_
_
M
G
N
T
S
S
E
R
A
A
L
E
R
Chimpanzee
Pan troglodytes
XP_513749
272
30341
S6
_
_
M
G
N
T
T
S
D
R
V
S
G
E
R
Rhesus Macaque
Macaca mulatta
XP_001093423
272
30312
S6
_
_
M
G
N
T
T
S
D
R
V
S
G
E
R
Dog
Lupus familis
XP_543421
270
30281
S6
_
_
M
G
N
T
S
S
E
R
A
A
L
E
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9R078
270
30290
S6
_
_
M
G
N
T
S
S
E
R
A
A
L
E
R
Rat
Rattus norvegicus
P80386
270
30376
S6
_
_
M
G
N
T
S
S
E
R
A
A
L
E
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514296
285
32181
E21
E
S
V
G
R
L
G
E
E
G
L
A
G
S
G
Chicken
Gallus gallus
NP_001035001
273
30440
R8
M
G
N
T
S
S
E
R
A
G
L
E
R
H
G
Frog
Xenopus laevis
NP_001085572
266
29829
D17
V
P
H
K
V
R
R
D
S
T
G
A
A
S
K
Zebra Danio
Brachydanio rerio
NP_001002632
268
30343
S6
_
_
M
G
N
T
S
S
E
R
T
G
M
G
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610460
341
36399
N82
K
K
H
T
A
V
L
N
E
G
S
S
Q
E
D
Honey Bee
Apis mellifera
XP_393160
283
31818
R20
H
H
T
S
N
T
N
R
E
H
R
H
V
K
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797535
279
30846
A6
_
_
M
G
N
T
A
A
K
R
D
G
K
D
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SCY5
289
31974
V40
A
A
S
D
G
N
H
V
A
P
P
E
L
M
G
Baker's Yeast
Sacchar. cerevisiae
P34164
415
46386
K11
T
T
S
H
P
A
Q
K
K
Q
T
T
K
K
C
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
70.5
70.9
98.5
N.A.
96.6
96.3
N.A.
63.8
91.2
80.3
81.1
N.A.
43.9
50.1
N.A.
49.4
Protein Similarity:
100
82.3
82.3
98.8
N.A.
97.7
98.5
N.A.
71.9
94.8
87.7
89.6
N.A.
54.8
66
N.A.
65.2
P-Site Identity:
100
61.5
61.5
100
N.A.
100
100
N.A.
20
0
6.6
61.5
N.A.
13.3
20
N.A.
38.4
P-Site Similarity:
100
84.6
84.6
100
N.A.
100
100
N.A.
26.6
20
13.3
76.9
N.A.
33.3
40
N.A.
69.2
Percent
Protein Identity:
N.A.
N.A.
N.A.
32.8
28.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.7
39.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
0
0
7
7
7
7
14
0
27
40
7
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% C
% Asp:
0
0
0
7
0
0
0
7
14
0
7
0
0
7
7
% D
% Glu:
7
0
0
0
0
0
7
7
54
0
0
14
0
47
7
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
7
0
60
7
0
7
0
0
20
7
14
20
7
27
% G
% His:
7
7
14
7
0
0
7
0
0
7
0
7
0
7
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
7
7
0
7
0
0
0
7
14
0
0
0
14
14
7
% K
% Leu:
0
0
0
0
0
7
7
0
0
0
14
0
34
0
0
% L
% Met:
7
0
54
0
0
0
0
0
0
0
0
0
7
7
0
% M
% Asn:
0
0
7
0
60
7
7
7
0
0
0
0
0
0
0
% N
% Pro:
0
7
0
0
7
0
0
0
0
7
7
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
7
0
0
7
0
0
7
0
7
% Q
% Arg:
0
0
0
0
7
7
7
14
0
54
7
0
7
0
40
% R
% Ser:
0
7
14
7
7
7
34
47
7
0
7
20
0
14
0
% S
% Thr:
7
7
7
14
0
60
14
0
0
7
14
7
0
0
0
% T
% Val:
7
0
7
0
7
7
0
7
0
0
14
0
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
54
54
0
0
0
0
0
0
0
0
0
0
0
0
0
% _