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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PRKAB1 All Species: 38.79
Human Site: T85 Identified Species: 60.95
UniProt: Q9Y478 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.21
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y478 NP_006244.2 270 30382 T85 R P T V F R W T G G G K E V Y
Chimpanzee Pan troglodytes XP_513749 272 30341 S84 R P T V I R W S E G G K E V F
Rhesus Macaque Macaca mulatta XP_001093423 272 30312 S84 R P T V I R W S E G G K E V F
Dog Lupus familis XP_543421 270 30281 T85 R P T V F R W T G G G K E V Y
Cat Felis silvestris
Mouse Mus musculus Q9R078 270 30290 T85 R P T V F R W T G G G K E V Y
Rat Rattus norvegicus P80386 270 30376 T85 R P T V F R W T G G G K E V Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514296 285 32181 S97 R P T V I R W S E G G R E V F
Chicken Gallus gallus NP_001035001 273 30440 T88 R P T V F R W T G G G K E V Y
Frog Xenopus laevis NP_001085572 266 29829 T81 R P T V F R W T G G G K E I Y
Zebra Danio Brachydanio rerio NP_001002632 268 30343 T82 R P T V F R W T G A G K E V Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610460 341 36399 D162 L P T V L R W D G G G K N V T
Honey Bee Apis mellifera XP_393160 283 31818 E104 L P T V F K W E G G G K Q V Y
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797535 279 30846 E89 L P V V F R W E G G G K S V A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SCY5 289 31974 C109 I P T M I T W C H G G K E I A
Baker's Yeast Sacchar. cerevisiae P34164 415 46386 Q171 V P V E I R W Q Q G G S K V Y
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 70.5 70.9 98.5 N.A. 96.6 96.3 N.A. 63.8 91.2 80.3 81.1 N.A. 43.9 50.1 N.A. 49.4
Protein Similarity: 100 82.3 82.3 98.8 N.A. 97.7 98.5 N.A. 71.9 94.8 87.7 89.6 N.A. 54.8 66 N.A. 65.2
P-Site Identity: 100 73.3 73.3 100 N.A. 100 100 N.A. 66.6 100 93.3 93.3 N.A. 66.6 73.3 N.A. 66.6
P-Site Similarity: 100 86.6 86.6 100 N.A. 100 100 N.A. 86.6 100 100 93.3 N.A. 66.6 86.6 N.A. 66.6
Percent
Protein Identity: N.A. N.A. N.A. 32.8 28.1 N.A.
Protein Similarity: N.A. N.A. N.A. 48.7 39.5 N.A.
P-Site Identity: N.A. N.A. N.A. 46.6 46.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 60 53.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 14 % A
% Cys: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 7 0 0 0 14 20 0 0 0 74 0 0 % E
% Phe: 0 0 0 0 60 0 0 0 0 0 0 0 0 0 20 % F
% Gly: 0 0 0 0 0 0 0 0 67 94 100 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % H
% Ile: 7 0 0 0 34 0 0 0 0 0 0 0 0 14 0 % I
% Lys: 0 0 0 0 0 7 0 0 0 0 0 87 7 0 0 % K
% Leu: 20 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % N
% Pro: 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 7 7 0 0 0 7 0 0 % Q
% Arg: 67 0 0 0 0 87 0 0 0 0 0 7 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 20 0 0 0 7 7 0 0 % S
% Thr: 0 0 87 0 0 7 0 47 0 0 0 0 0 0 7 % T
% Val: 7 0 14 87 0 0 0 0 0 0 0 0 0 87 0 % V
% Trp: 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 60 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _