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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDR45
All Species:
15.45
Human Site:
S11
Identified Species:
28.33
UniProt:
Q9Y484
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y484
NP_001025067.1
360
39868
S11
Q
P
L
R
G
V
T
S
L
R
F
N
Q
D
Q
Chimpanzee
Pan troglodytes
XP_001141167
371
41025
S11
Q
P
L
R
G
V
T
S
L
R
F
N
Q
D
Q
Rhesus Macaque
Macaca mulatta
XP_001114123
326
36142
Dog
Lupus familis
XP_851475
360
39762
S11
Q
P
L
R
G
V
T
S
L
R
F
N
Q
D
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q91VM3
360
39769
S11
Q
P
L
R
G
V
T
S
L
H
F
N
Q
D
Q
Rat
Rattus norvegicus
Q5U2Y0
309
34568
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZL16
344
38071
Frog
Xenopus laevis
Q6DCV0
355
39215
R11
Q
R
G
V
N
G
L
R
F
N
Q
D
Q
S
C
Zebra Danio
Brachydanio rerio
Q7ZUX3
358
39623
F12
R
G
V
N
S
L
Q
F
N
Q
D
Q
S
C
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396197
345
37993
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790559
342
38268
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P50079
448
51217
S21
R
R
K
P
K
F
L
S
V
S
F
N
Q
D
D
Red Bread Mold
Neurospora crassa
Q96U88
461
50001
A19
N
Q
D
Y
S
C
L
A
V
G
T
S
K
G
F
Conservation
Percent
Protein Identity:
100
97
46.1
98
N.A.
97.7
84.1
N.A.
N.A.
46.3
87.5
90
N.A.
N.A.
58.6
N.A.
41.3
Protein Similarity:
100
97
62.2
99.4
N.A.
99.7
85.5
N.A.
N.A.
63
95
96.3
N.A.
N.A.
78
N.A.
54.7
P-Site Identity:
100
100
0
100
N.A.
93.3
0
N.A.
N.A.
0
13.3
0
N.A.
N.A.
0
N.A.
0
P-Site Similarity:
100
100
0
100
N.A.
93.3
0
N.A.
N.A.
0
20
26.6
N.A.
N.A.
0
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26.7
25.3
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.6
40.7
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
33.3
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
46.6
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
0
8
8
% C
% Asp:
0
0
8
0
0
0
0
0
0
0
8
8
0
39
8
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
8
0
8
8
0
39
0
0
0
16
% F
% Gly:
0
8
8
0
31
8
0
0
0
8
0
0
0
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
8
0
8
0
0
0
0
0
0
0
8
0
0
% K
% Leu:
0
0
31
0
0
8
24
0
31
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
8
8
0
0
0
8
8
0
39
0
0
0
% N
% Pro:
0
31
0
8
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
39
8
0
0
0
0
8
0
0
8
8
8
47
0
31
% Q
% Arg:
16
16
0
31
0
0
0
8
0
24
0
0
0
0
0
% R
% Ser:
0
0
0
0
16
0
0
39
0
8
0
8
8
8
0
% S
% Thr:
0
0
0
0
0
0
31
0
0
0
8
0
0
0
0
% T
% Val:
0
0
8
8
0
31
0
0
16
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _