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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDR45
All Species:
18.18
Human Site:
S127
Identified Species:
33.33
UniProt:
Q9Y484
Number Species:
12
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y484
NP_001025067.1
360
39868
S127
K
N
R
I
Y
V
Y
S
F
P
D
N
P
R
K
Chimpanzee
Pan troglodytes
XP_001141167
371
41025
F138
N
P
R
K
L
F
E
F
D
T
R
D
N
P
K
Rhesus Macaque
Macaca mulatta
XP_001114123
326
36142
I94
V
K
L
R
R
D
R
I
V
V
V
L
D
S
M
Dog
Lupus familis
XP_851475
360
39762
S127
R
N
R
I
Y
V
Y
S
F
P
D
S
P
R
K
Cat
Felis silvestris
Mouse
Mus musculus
Q91VM3
360
39769
S127
R
N
R
I
Y
V
Y
S
F
P
D
S
P
R
K
Rat
Rattus norvegicus
Q5U2Y0
309
34568
S78
S
P
K
F
S
E
I
S
V
L
I
W
D
D
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZL16
344
38071
V113
K
L
R
R
D
R
I
V
V
V
L
D
S
M
I
Frog
Xenopus laevis
Q6DCV0
355
39215
S122
K
N
R
I
Y
V
Y
S
F
P
D
N
P
T
K
Zebra Danio
Brachydanio rerio
Q7ZUX3
358
39623
S125
K
N
R
I
Y
V
Y
S
F
P
D
N
P
V
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396197
345
37993
E114
M
I
V
A
L
Q
R
E
I
H
V
F
S
F
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790559
342
38268
E111
G
A
T
P
K
F
A
E
N
T
V
L
I
W
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P50079
448
51217
D159
I
P
P
N
G
S
V
D
Y
V
V
C
S
S
K
Red Bread Mold
Neurospora crassa
Q96U88
461
50001
N150
I
D
T
S
P
N
P
N
A
I
C
A
L
S
P
Conservation
Percent
Protein Identity:
100
97
46.1
98
N.A.
97.7
84.1
N.A.
N.A.
46.3
87.5
90
N.A.
N.A.
58.6
N.A.
41.3
Protein Similarity:
100
97
62.2
99.4
N.A.
99.7
85.5
N.A.
N.A.
63
95
96.3
N.A.
N.A.
78
N.A.
54.7
P-Site Identity:
100
13.3
0
86.6
N.A.
86.6
6.6
N.A.
N.A.
13.3
93.3
93.3
N.A.
N.A.
0
N.A.
0
P-Site Similarity:
100
20
0
100
N.A.
100
13.3
N.A.
N.A.
20
93.3
93.3
N.A.
N.A.
0
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26.7
25.3
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.6
40.7
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
8
0
0
8
0
8
0
0
8
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
8
8
0
0
0
% C
% Asp:
0
8
0
0
8
8
0
8
8
0
39
16
16
8
8
% D
% Glu:
0
0
0
0
0
8
8
16
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
8
0
16
0
8
39
0
0
8
0
8
0
% F
% Gly:
8
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
16
8
0
39
0
0
16
8
8
8
8
0
8
0
8
% I
% Lys:
31
8
8
8
8
0
0
0
0
0
0
0
0
0
54
% K
% Leu:
0
8
8
0
16
0
0
0
0
8
8
16
8
0
0
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
0
0
8
8
% M
% Asn:
8
39
0
8
0
8
0
8
8
0
0
24
8
0
0
% N
% Pro:
0
24
8
8
8
0
8
0
0
39
0
0
39
8
16
% P
% Gln:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% Q
% Arg:
16
0
54
16
8
8
16
0
0
0
8
0
0
24
0
% R
% Ser:
8
0
0
8
8
8
0
47
0
0
0
16
24
24
0
% S
% Thr:
0
0
16
0
0
0
0
0
0
16
0
0
0
8
0
% T
% Val:
8
0
8
0
0
39
8
8
24
24
31
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
8
0
8
0
% W
% Tyr:
0
0
0
0
39
0
39
0
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _