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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ATP6V0A2 All Species: 15.45
Human Site: S492 Identified Species: 28.33
UniProt: Q9Y487 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y487 NP_036595.2 856 98082 S492 V S A M Y S S S H P P A E H K
Chimpanzee Pan troglodytes XP_001165034 837 96375 S477 K S L N I F G S S W S V R P M
Rhesus Macaque Macaca mulatta XP_001098750 804 92087 S440 V S A M Y T S S H P P A E R K
Dog Lupus familis XP_543370 854 97888 S492 V S A M Y S S S H A L A E H R
Cat Felis silvestris
Mouse Mus musculus P15920 856 98127 S492 V S A M Y S S S H S P E E Q R
Rat Rattus norvegicus P25286 838 96309 S478 S L N I F G S S W S V R P M F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507655 845 96915 A481 V S A M Y V P A K A A E G V N
Chicken Gallus gallus Q9I8D0 838 95966 S478 S L N M F G S S W S V R P M F
Frog Xenopus laevis Q8AVM5 831 95538 S477 K A L N L F G S S W S V R P M
Zebra Danio Brachydanio rerio NP_001116219 849 97474 G486 S L N I F G S G W N V S A M F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P30628 905 103383 I524 N T I P E S V I D Y Y L D D E
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32563 840 95510 D481 Y T G F L Y N D I F S K T M T
Red Bread Mold Neurospora crassa Q01290 856 97974 F487 G L I Y N D V F S K S M T L F
Conservation
Percent
Protein Identity: 100 53.1 92 94.7 N.A. 91.5 53.1 N.A. 78.5 52.7 52.5 68.3 N.A. N.A. N.A. 44.4 N.A.
Protein Similarity: 100 70.7 92.9 97.5 N.A. 96.2 70.9 N.A. 86.6 70.2 70.5 81.1 N.A. N.A. N.A. 62.9 N.A.
P-Site Identity: 100 13.3 86.6 80 N.A. 73.3 13.3 N.A. 33.3 20 6.6 6.6 N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: 100 13.3 93.3 86.6 N.A. 80 26.6 N.A. 40 26.6 13.3 26.6 N.A. N.A. N.A. 26.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 37 40.8
Protein Similarity: N.A. N.A. N.A. N.A. 55.7 60.1
P-Site Identity: N.A. N.A. N.A. N.A. 0 0
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 0
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 39 0 0 0 0 8 0 16 8 24 8 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 8 0 8 8 0 0 0 8 8 0 % D
% Glu: 0 0 0 0 8 0 0 0 0 0 0 16 31 0 8 % E
% Phe: 0 0 0 8 24 16 0 8 0 8 0 0 0 0 31 % F
% Gly: 8 0 8 0 0 24 16 8 0 0 0 0 8 0 0 % G
% His: 0 0 0 0 0 0 0 0 31 0 0 0 0 16 0 % H
% Ile: 0 0 16 16 8 0 0 8 8 0 0 0 0 0 0 % I
% Lys: 16 0 0 0 0 0 0 0 8 8 0 8 0 0 16 % K
% Leu: 0 31 16 0 16 0 0 0 0 0 8 8 0 8 0 % L
% Met: 0 0 0 47 0 0 0 0 0 0 0 8 0 31 16 % M
% Asn: 8 0 24 16 8 0 8 0 0 8 0 0 0 0 8 % N
% Pro: 0 0 0 8 0 0 8 0 0 16 24 0 16 16 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 16 16 8 16 % R
% Ser: 24 47 0 0 0 31 54 62 24 24 31 8 0 0 0 % S
% Thr: 0 16 0 0 0 8 0 0 0 0 0 0 16 0 8 % T
% Val: 39 0 0 0 0 8 16 0 0 0 24 16 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 24 16 0 0 0 0 0 % W
% Tyr: 8 0 0 8 39 8 0 0 0 8 8 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _