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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TLN1 All Species: 31.82
Human Site: S423 Identified Species: 77.78
UniProt: Q9Y490 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y490 NP_006280.3 2541 269767 S423 E S T M L E D S V S P K K S T
Chimpanzee Pan troglodytes XP_001173465 2543 271676 S426 E S T M L E E S V S P K K S T
Rhesus Macaque Macaca mulatta XP_001084941 2455 260897 S423 E S T M L E D S V S P K K S T
Dog Lupus familis XP_531990 2541 269745 S423 E S T M L E D S V S P K K S T
Cat Felis silvestris
Mouse Mus musculus P26039 2541 269815 S423 E S T M L E D S V S P K K S T
Rat Rattus norvegicus NP_001034114 2541 269654 S423 E S T M L E D S V S P K K S T
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P54939 2541 271823 S423 E S T M L E D S V S P K K S T
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001009560 2538 270620 S419 E S T M L E D S V S P K K S T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_391944 2484 265783 A380 A L L S T I T A G H E V I H I
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785184 2554 274185 N437 E S L L F E E N V S A T R A R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 76 95.2 99.2 N.A. 98.6 98.6 N.A. N.A. 89 N.A. 83 N.A. N.A. 53.3 N.A. 59.7
Protein Similarity: 100 88.4 95.7 99.7 N.A. 99.5 99.5 N.A. N.A. 94.7 N.A. 91.6 N.A. N.A. 69.8 N.A. 75.4
P-Site Identity: 100 93.3 100 100 N.A. 100 100 N.A. N.A. 100 N.A. 100 N.A. N.A. 0 N.A. 33.3
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 100 N.A. 100 N.A. N.A. 6.6 N.A. 66.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 0 0 0 0 10 0 0 10 0 0 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 70 0 0 0 0 0 0 0 0 % D
% Glu: 90 0 0 0 0 90 20 0 0 0 10 0 0 0 0 % E
% Phe: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 10 0 0 0 10 0 % H
% Ile: 0 0 0 0 0 10 0 0 0 0 0 0 10 0 10 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 80 80 0 0 % K
% Leu: 0 10 20 10 80 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 80 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 80 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 10 % R
% Ser: 0 90 0 10 0 0 0 80 0 90 0 0 0 80 0 % S
% Thr: 0 0 80 0 10 0 10 0 0 0 0 10 0 0 80 % T
% Val: 0 0 0 0 0 0 0 0 90 0 0 10 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _