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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: JRKL All Species: 16.36
Human Site: S461 Identified Species: 60
UniProt: Q9Y4A0 Number Species: 6
    Phosphosite Substitution
    Charge Score: 0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y4A0 NP_003763.2 524 59912 S461 Q G Q A D E S S E N E E E E I
Chimpanzee Pan troglodytes XP_001149039 556 61639 A491 E V A W E Q A A V A F D A V L
Rhesus Macaque Macaca mulatta XP_001094262 524 59983 S461 Q G Q T D E S S E N E E E E I
Dog Lupus familis XP_533970 524 59786 S461 Q G Q T D E S S E N E E E E I
Cat Felis silvestris
Mouse Mus musculus B2RRL2 523 59692 S460 Q G Q T D E S S E N D E E R I
Rat Rattus norvegicus NP_001101592 524 59808 S461 Q G Q T D E S S E N D E E G I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510370 517 57676 E446 G D D S S D N E E E G E A G L
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 35 99 95.6 N.A. 93.8 93.3 N.A. 62.9 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 53.4 99.4 97.7 N.A. 95.8 95.9 N.A. 78.2 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 0 93.3 93.3 N.A. 80 80 N.A. 13.3 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 46.6 93.3 93.3 N.A. 86.6 86.6 N.A. 40 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 15 15 0 0 15 15 0 15 0 0 29 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 15 15 0 72 15 0 0 0 0 29 15 0 0 0 % D
% Glu: 15 0 0 0 15 72 0 15 86 15 43 86 72 43 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 15 0 0 0 0 % F
% Gly: 15 72 0 0 0 0 0 0 0 0 15 0 0 29 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 72 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 29 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 15 0 0 72 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 72 0 72 0 0 15 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 15 0 % R
% Ser: 0 0 0 15 15 0 72 72 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 58 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 15 0 0 0 0 0 0 15 0 0 0 0 15 0 % V
% Trp: 0 0 0 15 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _