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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NFE2L3
All Species:
12.12
Human Site:
T451
Identified Species:
26.67
UniProt:
Q9Y4A8
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y4A8
NP_004280.5
694
76154
T451
E
G
A
I
G
Y
C
T
D
H
E
S
S
S
H
Chimpanzee
Pan troglodytes
XP_519002
692
75934
T451
D
G
A
I
G
Y
C
T
D
H
E
S
S
S
H
Rhesus Macaque
Macaca mulatta
XP_001094650
693
76199
D451
G
A
T
G
Y
C
T
D
H
E
S
S
S
H
H
Dog
Lupus familis
XP_539481
659
72712
S416
E
G
A
T
G
S
S
S
D
L
E
S
L
S
H
Cat
Felis silvestris
Mouse
Mus musculus
Q9WTM4
660
72689
G429
C
H
D
L
G
A
V
G
G
C
Y
P
E
P
H
Rat
Rattus norvegicus
O54968
604
67684
H397
G
P
K
A
Q
P
T
H
S
S
G
D
T
V
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509998
566
61654
P359
D
P
E
T
P
G
K
P
T
F
R
H
V
L
H
Chicken
Gallus gallus
Q5ZL67
772
85168
S527
E
E
G
A
V
G
Y
S
S
D
S
E
N
V
D
Frog
Xenopus laevis
NP_001080013
718
79943
G475
S
S
S
F
S
E
E
G
A
V
G
Y
S
S
D
Zebra Danio
Brachydanio rerio
XP_001920265
797
88024
T544
E
G
A
V
G
Y
S
T
D
S
E
A
A
T
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P20482
1383
147394
Q1068
S
K
D
Y
H
H
H
Q
P
Y
G
M
G
A
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.1
93.2
72.7
N.A.
68.3
26.5
N.A.
43.9
33.9
35.7
33.1
N.A.
20.6
N.A.
N.A.
N.A.
Protein Similarity:
100
99.1
96.5
80.9
N.A.
77.3
43
N.A.
56.9
52.4
52.6
49.5
N.A.
32.4
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
20
60
N.A.
13.3
0
N.A.
6.6
6.6
13.3
53.3
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
20
66.6
N.A.
20
6.6
N.A.
13.3
20
20
80
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
37
19
0
10
0
0
10
0
0
10
10
10
10
% A
% Cys:
10
0
0
0
0
10
19
0
0
10
0
0
0
0
0
% C
% Asp:
19
0
19
0
0
0
0
10
37
10
0
10
0
0
19
% D
% Glu:
37
10
10
0
0
10
10
0
0
10
37
10
10
0
0
% E
% Phe:
0
0
0
10
0
0
0
0
0
10
0
0
0
0
0
% F
% Gly:
19
37
10
10
46
19
0
19
10
0
28
0
10
0
0
% G
% His:
0
10
0
0
10
10
10
10
10
19
0
10
0
10
55
% H
% Ile:
0
0
0
19
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
10
10
0
0
0
10
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
10
0
0
0
0
0
10
0
0
10
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% N
% Pro:
0
19
0
0
10
10
0
10
10
0
0
10
0
10
0
% P
% Gln:
0
0
0
0
10
0
0
10
0
0
0
0
0
0
10
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% R
% Ser:
19
10
10
0
10
10
19
19
19
19
19
37
37
37
10
% S
% Thr:
0
0
10
19
0
0
19
28
10
0
0
0
10
10
0
% T
% Val:
0
0
0
10
10
0
10
0
0
10
0
0
10
19
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
10
28
10
0
0
10
10
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _