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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RAD54L2
All Species:
34.24
Human Site:
Y591
Identified Species:
68.48
UniProt:
Q9Y4B4
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y4B4
NP_055921.2
1467
162796
Y591
S
K
I
Q
R
D
L
Y
T
Q
F
M
D
R
F
Chimpanzee
Pan troglodytes
XP_001169759
1467
162690
Y591
S
K
I
Q
R
D
L
Y
T
Q
F
M
D
R
F
Rhesus Macaque
Macaca mulatta
XP_001096767
1467
162593
Y591
S
K
I
Q
R
D
L
Y
T
Q
F
M
D
R
F
Dog
Lupus familis
XP_533811
1467
162638
Y591
S
K
I
Q
R
D
L
Y
T
Q
F
M
D
R
F
Cat
Felis silvestris
Mouse
Mus musculus
Q99NG0
1466
162522
Y590
S
Q
I
Q
R
D
L
Y
T
Q
F
M
D
R
F
Rat
Rattus norvegicus
NP_001127992
1299
144800
G455
E
K
A
L
C
R
P
G
P
D
V
V
I
C
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506490
1466
162300
Y587
S
K
I
Q
R
A
L
Y
T
E
F
M
N
R
F
Chicken
Gallus gallus
XP_414277
1473
163359
Y600
S
K
I
Q
R
A
L
Y
T
E
F
M
N
R
F
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_687332
1437
158796
R598
V
R
L
S
R
L
Q
R
A
L
Y
T
E
F
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611885
1669
187351
Y697
T
A
F
Q
R
K
L
Y
D
T
F
M
T
D
V
Honey Bee
Apis mellifera
XP_397192
2507
279667
Y829
T
S
H
Q
R
K
L
Y
D
T
F
M
N
Q
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783354
1637
178336
Y678
T
S
F
Q
R
G
L
Y
I
R
F
M
Q
C
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99
97.2
N.A.
95.9
84.8
N.A.
79.7
78.8
N.A.
59.1
N.A.
27
25
N.A.
41.9
Protein Similarity:
100
99.8
99.3
98.5
N.A.
97.3
86.3
N.A.
86.9
87
N.A.
70.8
N.A.
42.9
38.9
N.A.
55.8
P-Site Identity:
100
100
100
100
N.A.
93.3
6.6
N.A.
80
80
N.A.
6.6
N.A.
40
40
N.A.
46.6
P-Site Similarity:
100
100
100
100
N.A.
100
13.3
N.A.
93.3
93.3
N.A.
33.3
N.A.
46.6
60
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
9
0
0
17
0
0
9
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
9
0
0
0
0
0
0
0
0
17
0
% C
% Asp:
0
0
0
0
0
42
0
0
17
9
0
0
42
9
9
% D
% Glu:
9
0
0
0
0
0
0
0
0
17
0
0
9
0
0
% E
% Phe:
0
0
17
0
0
0
0
0
0
0
84
0
0
9
67
% F
% Gly:
0
0
0
0
0
9
0
9
0
0
0
0
0
0
0
% G
% His:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
59
0
0
0
0
0
9
0
0
0
9
0
0
% I
% Lys:
0
59
0
0
0
17
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
9
9
0
9
84
0
0
9
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
84
0
0
9
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
25
0
0
% N
% Pro:
0
0
0
0
0
0
9
0
9
0
0
0
0
0
0
% P
% Gln:
0
9
0
84
0
0
9
0
0
42
0
0
9
9
0
% Q
% Arg:
0
9
0
0
92
9
0
9
0
9
0
0
0
59
0
% R
% Ser:
59
17
0
9
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
25
0
0
0
0
0
0
0
59
17
0
9
9
0
0
% T
% Val:
9
0
0
0
0
0
0
0
0
0
9
9
0
0
17
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
84
0
0
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _