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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: VPRBP All Species: 23.64
Human Site: S1161 Identified Species: 43.33
UniProt: Q9Y4B6 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y4B6 NP_055518.1 1507 169007 S1161 A T W S Q P L S A L W G M K S
Chimpanzee Pan troglodytes XP_001169544 1507 169049 S1161 A T W S Q P L S A L W G M K S
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_533812 783 87243 A476 I G T K G D I A H I Y D I Q T
Cat Felis silvestris
Mouse Mus musculus Q80TR8 1506 168913 S1160 A T W S Q P L S A L W G M K S
Rat Rattus norvegicus XP_002727180 1506 168898 S1160 A T W S Q P L S A L W G M K S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506711 1059 118215 Q752 V E F S K H S Q D R V I G T K
Chicken Gallus gallus XP_414265 1505 168771 S1157 A T W S Q P L S A L W G M K S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_002663313 425 46782 L118 N H L L S K G L T D T A T T L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W2F2 1544 172067 S1221 S F W R T P T S I L W S I A D
Honey Bee Apis mellifera XP_396132 1425 160241 E1118 K L S L E N V E Y V E F G K L
Nematode Worm Caenorhab. elegans Q21106 1701 192878 S1156 S A F S R P L S A L W R L G E
Sea Urchin Strong. purpuratus XP_795660 1528 169456 H1221 L T S S T W S H P M S A L W G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9M086 1883 205433 A1538 S D V Q L W D A S S I T G G P
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.9 N.A. 51.5 N.A. 98.2 98.4 N.A. 65.7 93.7 N.A. 21.2 N.A. 34.8 43.3 30.9 50.1
Protein Similarity: 100 99.9 N.A. 51.6 N.A. 99 99.2 N.A. 68.1 97.3 N.A. 24.2 N.A. 52.7 62.5 50.1 67.2
P-Site Identity: 100 100 N.A. 0 N.A. 100 100 N.A. 6.6 100 N.A. 0 N.A. 33.3 6.6 46.6 13.3
P-Site Similarity: 100 100 N.A. 46.6 N.A. 100 100 N.A. 20 100 N.A. 0 N.A. 46.6 26.6 73.3 26.6
Percent
Protein Identity: N.A. N.A. N.A. 25.6 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 43.7 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 39 8 0 0 0 0 0 16 47 0 0 16 0 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 0 0 8 8 0 8 8 0 8 0 0 8 % D
% Glu: 0 8 0 0 8 0 0 8 0 0 8 0 0 0 8 % E
% Phe: 0 8 16 0 0 0 0 0 0 0 0 8 0 0 0 % F
% Gly: 0 8 0 0 8 0 8 0 0 0 0 39 24 16 8 % G
% His: 0 8 0 0 0 8 0 8 8 0 0 0 0 0 0 % H
% Ile: 8 0 0 0 0 0 8 0 8 8 8 8 16 0 0 % I
% Lys: 8 0 0 8 8 8 0 0 0 0 0 0 0 47 8 % K
% Leu: 8 8 8 16 8 0 47 8 0 54 0 0 16 0 16 % L
% Met: 0 0 0 0 0 0 0 0 0 8 0 0 39 0 0 % M
% Asn: 8 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 54 0 0 8 0 0 0 0 0 8 % P
% Gln: 0 0 0 8 39 0 0 8 0 0 0 0 0 8 0 % Q
% Arg: 0 0 0 8 8 0 0 0 0 8 0 8 0 0 0 % R
% Ser: 24 0 16 62 8 0 16 54 8 8 8 8 0 0 39 % S
% Thr: 0 47 8 0 16 0 8 0 8 0 8 8 8 16 8 % T
% Val: 8 0 8 0 0 0 8 0 0 8 8 0 0 0 0 % V
% Trp: 0 0 47 0 0 16 0 0 0 0 54 0 0 8 0 % W
% Tyr: 0 0 0 0 0 0 0 0 8 0 8 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _