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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: VPRBP All Species: 23.94
Human Site: S1476 Identified Species: 43.89
UniProt: Q9Y4B6 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y4B6 NP_055518.1 1507 169007 S1476 E D G E D E D S D A D E E V E
Chimpanzee Pan troglodytes XP_001169544 1507 169049 S1476 E D G E D E D S D A D E E V E
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_533812 783 87243 D753 D G E D E D S D A D E E V E L
Cat Felis silvestris
Mouse Mus musculus Q80TR8 1506 168913 S1475 E E G E D E D S D A D E E V E
Rat Rattus norvegicus XP_002727180 1506 168898 S1475 E E G E D E D S D A D E E V E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506711 1059 118215 E1029 E L A N L I E E G D E A E D E
Chicken Gallus gallus XP_414265 1505 168771 S1474 D E G E D E D S D A D E E V E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_002663313 425 46782 T395 S C H S S A I T H L E P S R W
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W2F2 1544 172067 S1512 D D G E P L D S D D D S D D D
Honey Bee Apis mellifera XP_396132 1425 160241 S1395 D S G D G D D S G D D M T H Y
Nematode Worm Caenorhab. elegans Q21106 1701 192878 G1508 D D D E D G E G D P D F D M G
Sea Urchin Strong. purpuratus XP_795660 1528 169456 G1498 I G D L A G N G G G G D F S G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9M086 1883 205433 G1851 E G E N E D D G N G E D E D D
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.9 N.A. 51.5 N.A. 98.2 98.4 N.A. 65.7 93.7 N.A. 21.2 N.A. 34.8 43.3 30.9 50.1
Protein Similarity: 100 99.9 N.A. 51.6 N.A. 99 99.2 N.A. 68.1 97.3 N.A. 24.2 N.A. 52.7 62.5 50.1 67.2
P-Site Identity: 100 100 N.A. 6.6 N.A. 93.3 93.3 N.A. 20 86.6 N.A. 0 N.A. 46.6 26.6 33.3 0
P-Site Similarity: 100 100 N.A. 40 N.A. 100 100 N.A. 33.3 100 N.A. 13.3 N.A. 66.6 46.6 60 13.3
Percent
Protein Identity: N.A. N.A. N.A. 25.6 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 43.7 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 20 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 60 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 0 8 8 0 0 8 39 0 8 0 0 0 % A
% Cys: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 39 31 16 16 47 24 62 8 54 31 62 16 16 24 16 % D
% Glu: 47 24 16 54 16 39 16 8 0 0 31 47 54 8 47 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 8 8 0 0 % F
% Gly: 0 24 54 0 8 16 0 24 24 16 8 0 0 0 16 % G
% His: 0 0 8 0 0 0 0 0 8 0 0 0 0 8 0 % H
% Ile: 8 0 0 0 0 8 8 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 8 0 8 8 8 0 0 0 8 0 0 0 0 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 8 0 8 0 % M
% Asn: 0 0 0 16 0 0 8 0 8 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 8 0 0 0 0 8 0 8 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % R
% Ser: 8 8 0 8 8 0 8 54 0 0 0 8 8 8 0 % S
% Thr: 0 0 0 0 0 0 0 8 0 0 0 0 8 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 8 39 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _