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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: VPRBP All Species: 17.88
Human Site: S255 Identified Species: 32.78
UniProt: Q9Y4B6 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y4B6 NP_055518.1 1507 169007 S255 K T S S R V N S T T K P E D G
Chimpanzee Pan troglodytes XP_001169544 1507 169049 S255 K T S S R V N S T T K P E D G
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_533812 783 87243
Cat Felis silvestris
Mouse Mus musculus Q80TR8 1506 168913 S254 K T S S R V N S A T K P E E G
Rat Rattus norvegicus XP_002727180 1506 168898 S254 K T S S R V N S A T K P E E G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506711 1059 118215
Chicken Gallus gallus XP_414265 1505 168771 S252 K T S S R V N S A T K L N D G
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_002663313 425 46782
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W2F2 1544 172067 T317 N L S A D S S T A G M L S W V
Honey Bee Apis mellifera XP_396132 1425 160241 P217 N F N N Q I T P S K A Q N A Y
Nematode Worm Caenorhab. elegans Q21106 1701 192878 E251 D G S T K E N E K T F V Q S T
Sea Urchin Strong. purpuratus XP_795660 1528 169456 N265 G S T N E A R N S V K D D S D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9M086 1883 205433 D361 R L L V R D R D L S K I S D G
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.9 N.A. 51.5 N.A. 98.2 98.4 N.A. 65.7 93.7 N.A. 21.2 N.A. 34.8 43.3 30.9 50.1
Protein Similarity: 100 99.9 N.A. 51.6 N.A. 99 99.2 N.A. 68.1 97.3 N.A. 24.2 N.A. 52.7 62.5 50.1 67.2
P-Site Identity: 100 100 N.A. 0 N.A. 86.6 86.6 N.A. 0 80 N.A. 0 N.A. 6.6 0 20 6.6
P-Site Similarity: 100 100 N.A. 0 N.A. 93.3 93.3 N.A. 0 80 N.A. 0 N.A. 26.6 33.3 40 46.6
Percent
Protein Identity: N.A. N.A. N.A. 25.6 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 43.7 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 26.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 40 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 0 8 0 0 31 0 8 0 0 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 0 0 8 8 0 8 0 0 0 8 8 31 8 % D
% Glu: 0 0 0 0 8 8 0 8 0 0 0 0 31 16 0 % E
% Phe: 0 8 0 0 0 0 0 0 0 0 8 0 0 0 0 % F
% Gly: 8 8 0 0 0 0 0 0 0 8 0 0 0 0 47 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 8 0 0 0 0 0 8 0 0 0 % I
% Lys: 39 0 0 0 8 0 0 0 8 8 54 0 0 0 0 % K
% Leu: 0 16 8 0 0 0 0 0 8 0 0 16 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % M
% Asn: 16 0 8 16 0 0 47 8 0 0 0 0 16 0 0 % N
% Pro: 0 0 0 0 0 0 0 8 0 0 0 31 0 0 0 % P
% Gln: 0 0 0 0 8 0 0 0 0 0 0 8 8 0 0 % Q
% Arg: 8 0 0 0 47 0 16 0 0 0 0 0 0 0 0 % R
% Ser: 0 8 54 39 0 8 8 39 16 8 0 0 16 16 0 % S
% Thr: 0 39 8 8 0 0 8 8 16 47 0 0 0 0 8 % T
% Val: 0 0 0 8 0 39 0 0 0 8 0 8 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _