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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: VPRBP All Species: 16.97
Human Site: S946 Identified Species: 31.11
UniProt: Q9Y4B6 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y4B6 NP_055518.1 1507 169007 S946 P L A L P G P S Y A G N S P L
Chimpanzee Pan troglodytes XP_001169544 1507 169049 S946 P L A L P G P S Y A G N S P L
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_533812 783 87243 P264 H G A Y S Q S P A I K K Q L D
Cat Felis silvestris
Mouse Mus musculus Q80TR8 1506 168913 S945 S L P L P G P S Y A G N S P L
Rat Rattus norvegicus XP_002727180 1506 168898 S945 S L A L P G P S Y A G N S P L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506711 1059 118215 Q540 R K T R V L R Q K S D H G A Y
Chicken Gallus gallus XP_414265 1505 168771 S942 P L A L P G P S Y A S N S P L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_002663313 425 46782
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W2F2 1544 172067 A1009 A G A G G S N A G D G V S I P
Honey Bee Apis mellifera XP_396132 1425 160241 L905 S Q V D K Q P L V N Q I N C H
Nematode Worm Caenorhab. elegans Q21106 1701 192878 M944 A S L S S P A M A T R S H S T
Sea Urchin Strong. purpuratus XP_795660 1528 169456 R1009 T A S L P P P R I V F G P D S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9M086 1883 205433 I1322 S S V P G K R I D L G E R R N
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.9 N.A. 51.5 N.A. 98.2 98.4 N.A. 65.7 93.7 N.A. 21.2 N.A. 34.8 43.3 30.9 50.1
Protein Similarity: 100 99.9 N.A. 51.6 N.A. 99 99.2 N.A. 68.1 97.3 N.A. 24.2 N.A. 52.7 62.5 50.1 67.2
P-Site Identity: 100 100 N.A. 6.6 N.A. 86.6 93.3 N.A. 0 93.3 N.A. 0 N.A. 20 6.6 0 20
P-Site Similarity: 100 100 N.A. 6.6 N.A. 86.6 93.3 N.A. 13.3 93.3 N.A. 0 N.A. 26.6 13.3 6.6 26.6
Percent
Protein Identity: N.A. N.A. N.A. 25.6 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 43.7 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 6.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 16 8 47 0 0 0 8 8 16 39 0 0 0 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % C
% Asp: 0 0 0 8 0 0 0 0 8 8 8 0 0 8 8 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % F
% Gly: 0 16 0 8 16 39 0 0 8 0 47 8 8 0 0 % G
% His: 8 0 0 0 0 0 0 0 0 0 0 8 8 0 8 % H
% Ile: 0 0 0 0 0 0 0 8 8 8 0 8 0 8 0 % I
% Lys: 0 8 0 0 8 8 0 0 8 0 8 8 0 0 0 % K
% Leu: 0 39 8 47 0 8 0 8 0 8 0 0 0 8 39 % L
% Met: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 8 0 0 8 0 39 8 0 8 % N
% Pro: 24 0 8 8 47 16 54 8 0 0 0 0 8 39 8 % P
% Gln: 0 8 0 0 0 16 0 8 0 0 8 0 8 0 0 % Q
% Arg: 8 0 0 8 0 0 16 8 0 0 8 0 8 8 0 % R
% Ser: 31 16 8 8 16 8 8 39 0 8 8 8 47 8 8 % S
% Thr: 8 0 8 0 0 0 0 0 0 8 0 0 0 0 8 % T
% Val: 0 0 16 0 8 0 0 0 8 8 0 8 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 8 0 0 0 0 39 0 0 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _