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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPRBP
All Species:
23.03
Human Site:
Y1223
Identified Species:
42.22
UniProt:
Q9Y4B6
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y4B6
NP_055518.1
1507
169007
Y1223
N
P
D
L
A
N
N
Y
K
R
N
C
A
T
F
Chimpanzee
Pan troglodytes
XP_001169544
1507
169049
Y1223
N
P
D
L
A
N
N
Y
K
R
N
C
A
T
F
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_533812
783
87243
I538
F
D
K
F
N
M
N
I
S
G
V
F
H
P
N
Cat
Felis silvestris
Mouse
Mus musculus
Q80TR8
1506
168913
Y1222
N
P
D
L
A
N
N
Y
K
R
N
C
A
T
F
Rat
Rattus norvegicus
XP_002727180
1506
168898
Y1222
N
P
D
L
A
N
N
Y
K
R
N
C
A
T
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506711
1059
118215
A814
W
D
V
R
S
A
Q
A
I
H
K
F
D
K
F
Chicken
Gallus gallus
XP_414265
1505
168771
Y1219
N
P
D
L
A
N
N
Y
K
K
N
C
A
T
F
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002663313
425
46782
P180
A
R
L
G
G
H
T
P
H
H
P
Q
P
R
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W2F2
1544
172067
Y1283
T
P
T
I
P
N
L
Y
T
K
N
R
A
T
L
Honey Bee
Apis mellifera
XP_396132
1425
160241
W1180
V
L
H
D
G
I
L
W
D
A
N
S
G
K
Q
Nematode Worm
Caenorhab. elegans
Q21106
1701
192878
Y1218
S
G
I
D
G
L
Q
Y
E
K
N
Y
A
S
F
Sea Urchin
Strong. purpuratus
XP_795660
1528
169456
S1283
T
L
Q
D
G
Q
L
S
N
N
Y
T
N
N
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M086
1883
205433
N1600
T
V
T
S
S
R
S
N
P
Y
S
L
V
H
F
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
N.A.
51.5
N.A.
98.2
98.4
N.A.
65.7
93.7
N.A.
21.2
N.A.
34.8
43.3
30.9
50.1
Protein Similarity:
100
99.9
N.A.
51.6
N.A.
99
99.2
N.A.
68.1
97.3
N.A.
24.2
N.A.
52.7
62.5
50.1
67.2
P-Site Identity:
100
100
N.A.
6.6
N.A.
100
100
N.A.
6.6
93.3
N.A.
0
N.A.
40
6.6
26.6
0
P-Site Similarity:
100
100
N.A.
6.6
N.A.
100
100
N.A.
13.3
100
N.A.
6.6
N.A.
53.3
13.3
53.3
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
43.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
39
8
0
8
0
8
0
0
54
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
39
0
0
8
% C
% Asp:
0
16
39
24
0
0
0
0
8
0
0
0
8
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% E
% Phe:
8
0
0
8
0
0
0
0
0
0
0
16
0
0
62
% F
% Gly:
0
8
0
8
31
0
0
0
0
8
0
0
8
0
0
% G
% His:
0
0
8
0
0
8
0
0
8
16
0
0
8
8
0
% H
% Ile:
0
0
8
8
0
8
0
8
8
0
0
0
0
0
0
% I
% Lys:
0
0
8
0
0
0
0
0
39
24
8
0
0
16
0
% K
% Leu:
0
16
8
39
0
8
24
0
0
0
0
8
0
0
8
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
39
0
0
0
8
47
47
8
8
8
62
0
8
8
8
% N
% Pro:
0
47
0
0
8
0
0
8
8
0
8
0
8
8
8
% P
% Gln:
0
0
8
0
0
8
16
0
0
0
0
8
0
0
8
% Q
% Arg:
0
8
0
8
0
8
0
0
0
31
0
8
0
8
0
% R
% Ser:
8
0
0
8
16
0
8
8
8
0
8
8
0
8
0
% S
% Thr:
24
0
16
0
0
0
8
0
8
0
0
8
0
47
0
% T
% Val:
8
8
8
0
0
0
0
0
0
0
8
0
8
0
0
% V
% Trp:
8
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
54
0
8
8
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _