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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPRBP
All Species:
24.85
Human Site:
Y146
Identified Species:
45.56
UniProt:
Q9Y4B6
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y4B6
NP_055518.1
1507
169007
Y146
A
D
Q
P
L
R
T
Y
S
T
G
L
L
G
G
Chimpanzee
Pan troglodytes
XP_001169544
1507
169049
Y146
A
D
Q
P
L
R
T
Y
F
T
G
L
L
G
G
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_533812
783
87243
Cat
Felis silvestris
Mouse
Mus musculus
Q80TR8
1506
168913
Y146
A
D
Q
P
L
R
T
Y
S
T
G
L
L
G
G
Rat
Rattus norvegicus
XP_002727180
1506
168898
Y146
A
D
Q
P
L
R
T
Y
S
T
G
L
L
G
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506711
1059
118215
Chicken
Gallus gallus
XP_414265
1505
168771
Y146
A
D
Q
P
L
R
T
Y
A
T
G
L
L
G
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002663313
425
46782
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W2F2
1544
172067
A214
S
L
E
L
N
I
L
A
C
R
L
I
L
E
I
Honey Bee
Apis mellifera
XP_396132
1425
160241
A114
D
V
R
K
L
N
I
A
A
C
R
L
M
L
D
Nematode Worm
Caenorhab. elegans
Q21106
1701
192878
W155
F
I
P
R
L
Y
T
W
A
G
S
E
G
T
N
Sea Urchin
Strong. purpuratus
XP_795660
1528
169456
Y144
A
E
E
P
L
K
S
Y
A
T
G
L
L
A
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M086
1883
205433
Y193
D
F
E
M
L
K
T
Y
S
T
G
L
L
A
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
N.A.
51.5
N.A.
98.2
98.4
N.A.
65.7
93.7
N.A.
21.2
N.A.
34.8
43.3
30.9
50.1
Protein Similarity:
100
99.9
N.A.
51.6
N.A.
99
99.2
N.A.
68.1
97.3
N.A.
24.2
N.A.
52.7
62.5
50.1
67.2
P-Site Identity:
100
93.3
N.A.
0
N.A.
100
100
N.A.
0
93.3
N.A.
0
N.A.
6.6
13.3
13.3
53.3
P-Site Similarity:
100
93.3
N.A.
0
N.A.
100
100
N.A.
0
100
N.A.
0
N.A.
26.6
33.3
26.6
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
43.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
53.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
66.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
47
0
0
0
0
0
0
16
31
0
0
0
0
16
8
% A
% Cys:
0
0
0
0
0
0
0
0
8
8
0
0
0
0
0
% C
% Asp:
16
39
0
0
0
0
0
0
0
0
0
0
0
0
8
% D
% Glu:
0
8
24
0
0
0
0
0
0
0
0
8
0
8
0
% E
% Phe:
8
8
0
0
0
0
0
0
8
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
8
54
0
8
39
39
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
8
8
0
0
0
0
8
0
0
8
% I
% Lys:
0
0
0
8
0
16
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
8
0
8
70
0
8
0
0
0
8
62
62
8
8
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
0
0
0
8
8
0
0
0
0
0
0
0
0
8
% N
% Pro:
0
0
8
47
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
39
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
8
8
0
39
0
0
0
8
8
0
0
0
0
% R
% Ser:
8
0
0
0
0
0
8
0
31
0
8
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
54
0
0
54
0
0
0
8
0
% T
% Val:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
54
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _