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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPRBP
All Species:
36.36
Human Site:
Y419
Identified Species:
66.67
UniProt:
Q9Y4B6
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y4B6
NP_055518.1
1507
169007
Y419
G
V
S
M
C
L
Y
Y
L
S
Y
N
Q
D
A
Chimpanzee
Pan troglodytes
XP_001169544
1507
169049
Y419
G
V
S
M
C
L
Y
Y
L
S
Y
N
Q
D
A
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_533812
783
87243
Cat
Felis silvestris
Mouse
Mus musculus
Q80TR8
1506
168913
Y418
G
V
S
M
C
L
Y
Y
L
S
Y
N
Q
D
A
Rat
Rattus norvegicus
XP_002727180
1506
168898
Y418
G
V
S
M
C
L
Y
Y
L
S
Y
N
Q
D
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506711
1059
118215
D30
R
D
H
G
S
G
Q
D
M
V
P
I
L
T
R
Chicken
Gallus gallus
XP_414265
1505
168771
Y416
G
V
S
M
C
L
Y
Y
L
S
Y
N
Q
D
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002663313
425
46782
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W2F2
1544
172067
Y481
G
V
S
I
A
I
Y
Y
L
A
Y
C
E
D
A
Honey Bee
Apis mellifera
XP_396132
1425
160241
Y377
G
V
S
I
C
L
Y
Y
L
A
Y
C
E
D
A
Nematode Worm
Caenorhab. elegans
Q21106
1701
192878
Y414
G
V
V
T
C
L
Y
Y
I
A
Y
S
N
D
V
Sea Urchin
Strong. purpuratus
XP_795660
1528
169456
Y487
G
V
S
L
C
L
Y
Y
L
A
Y
N
E
D
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M086
1883
205433
T605
G
L
S
S
C
L
Y
T
I
G
S
L
Q
G
I
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
N.A.
51.5
N.A.
98.2
98.4
N.A.
65.7
93.7
N.A.
21.2
N.A.
34.8
43.3
30.9
50.1
Protein Similarity:
100
99.9
N.A.
51.6
N.A.
99
99.2
N.A.
68.1
97.3
N.A.
24.2
N.A.
52.7
62.5
50.1
67.2
P-Site Identity:
100
100
N.A.
0
N.A.
100
100
N.A.
0
100
N.A.
0
N.A.
60
73.3
53.3
73.3
P-Site Similarity:
100
100
N.A.
0
N.A.
100
100
N.A.
6.6
100
N.A.
0
N.A.
86.6
93.3
73.3
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
43.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
0
0
0
31
0
0
0
0
54
% A
% Cys:
0
0
0
0
70
0
0
0
0
0
0
16
0
0
0
% C
% Asp:
0
8
0
0
0
0
0
8
0
0
0
0
0
70
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
24
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
77
0
0
8
0
8
0
0
0
8
0
0
0
8
0
% G
% His:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
16
0
8
0
0
16
0
0
8
0
0
8
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
8
0
8
0
70
0
0
62
0
0
8
8
0
0
% L
% Met:
0
0
0
39
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
47
8
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
8
0
0
0
0
0
47
0
0
% Q
% Arg:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% R
% Ser:
0
0
70
8
8
0
0
0
0
39
8
8
0
0
0
% S
% Thr:
0
0
0
8
0
0
0
8
0
0
0
0
0
8
8
% T
% Val:
0
70
8
0
0
0
0
0
0
8
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
77
70
0
0
70
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _