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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RBM19 All Species: 22.42
Human Site: S423 Identified Species: 37.95
UniProt: Q9Y4C8 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y4C8 NP_001140170.1 960 107338 S423 E D L E K L F S K Y G P L S E
Chimpanzee Pan troglodytes XP_522578 961 107391 S423 E D L E K L F S K Y G P L S E
Rhesus Macaque Macaca mulatta XP_001106082 998 111078 S461 E D L E K L F S K Y G P L S E
Dog Lupus familis XP_543410 1176 130518 S426 E D L Q R L F S K F G P L S E
Cat Felis silvestris
Mouse Mus musculus Q8R3C6 952 106065 S421 E D L E K L F S A Y G P L S E
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001034357 957 107850 S435 E D L E K I F S K Y G P L S E
Frog Xenopus laevis P20397 651 70177 V138 E S E E E K A V A K K P T P A
Zebra Danio Brachydanio rerio NP_944597 926 104540 I402 A E S G R L F I R N M P Y T C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648337 918 103859 E385 E D L R K L F E Q F G P V V E
Honey Bee Apis mellifera XP_624611 816 93057 R303 E S I A E S G R M F I R N L S
Nematode Worm Caenorhab. elegans NP_502432 872 98025 R359 I L P G D E K R T K E G E E E
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002303703 784 87961 P271 R L F V R N L P Y T A I E D E
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q06106 887 101101 V374 P F G E L E E V H V A L D T R
Red Bread Mold Neurospora crassa Q7SG09 827 90390 N314 T S R L F L R N L S Y T V T E
Conservation
Percent
Protein Identity: 100 99.2 93 69.4 N.A. 81.6 N.A. N.A. N.A. 67.7 22.1 61 N.A. 39.9 43.5 34.5 N.A.
Protein Similarity: 100 99.4 93.7 73.4 N.A. 87.8 N.A. N.A. N.A. 79.7 36.5 74.4 N.A. 60.7 58.8 51.8 N.A.
P-Site Identity: 100 100 100 80 N.A. 93.3 N.A. N.A. N.A. 93.3 20 20 N.A. 60 6.6 6.6 N.A.
P-Site Similarity: 100 100 100 100 N.A. 93.3 N.A. N.A. N.A. 100 26.6 46.6 N.A. 80 26.6 6.6 N.A.
Percent
Protein Identity: 32.4 N.A. N.A. N.A. 29.2 31.2
Protein Similarity: 51.6 N.A. N.A. N.A. 47.4 49.7
P-Site Identity: 6.6 N.A. N.A. N.A. 6.6 13.3
P-Site Similarity: 13.3 N.A. N.A. N.A. 13.3 33.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 8 0 0 8 0 15 0 15 0 0 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % C
% Asp: 0 50 0 0 8 0 0 0 0 0 0 0 8 8 0 % D
% Glu: 65 8 8 50 15 15 8 8 0 0 8 0 15 8 72 % E
% Phe: 0 8 8 0 8 0 58 0 0 22 0 0 0 0 0 % F
% Gly: 0 0 8 15 0 0 8 0 0 0 50 8 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % H
% Ile: 8 0 8 0 0 8 0 8 0 0 8 8 0 0 0 % I
% Lys: 0 0 0 0 43 8 8 0 36 15 8 0 0 0 0 % K
% Leu: 0 15 50 8 8 58 8 0 8 0 0 8 43 8 0 % L
% Met: 0 0 0 0 0 0 0 0 8 0 8 0 0 0 0 % M
% Asn: 0 0 0 0 0 8 0 8 0 8 0 0 8 0 0 % N
% Pro: 8 0 8 0 0 0 0 8 0 0 0 65 0 8 0 % P
% Gln: 0 0 0 8 0 0 0 0 8 0 0 0 0 0 0 % Q
% Arg: 8 0 8 8 22 0 8 15 8 0 0 8 0 0 8 % R
% Ser: 0 22 8 0 0 8 0 43 0 8 0 0 0 43 8 % S
% Thr: 8 0 0 0 0 0 0 0 8 8 0 8 8 22 0 % T
% Val: 0 0 0 8 0 0 0 15 0 8 0 0 15 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 8 36 8 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _