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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RBM19 All Species: 14.85
Human Site: S493 Identified Species: 25.13
UniProt: Q9Y4C8 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y4C8 NP_001140170.1 960 107338 S493 E D A S A L G S S S Y K K K K
Chimpanzee Pan troglodytes XP_522578 961 107391 S493 E D A S A L G S S S Y K K K K
Rhesus Macaque Macaca mulatta XP_001106082 998 111078 S531 E D A S A L G S S S Y K K K K
Dog Lupus familis XP_543410 1176 130518 G495 S E D T D T Q G S S Y K K K K
Cat Felis silvestris
Mouse Mus musculus Q8R3C6 952 106065 G490 S Q E A N A P G S S Y K K K K
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001034357 957 107850 S505 E D I D A E E S S S Y K K Q K
Frog Xenopus laevis P20397 651 70177 G206 D D E E E Q Q G S A K R K K E
Zebra Danio Brachydanio rerio NP_944597 926 104540 H470 T F Q G R V L H V M A S R L K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648337 918 103859 S457 D L D E N D A S L S F K E K K
Honey Bee Apis mellifera XP_624611 816 93057 R371 D G S I L D G R M L H L L P A
Nematode Worm Caenorhab. elegans NP_502432 872 98025 R427 I A D T L A Q R L N V K K S D
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002303703 784 87961 A339 R L L H V M P A K Q K I L S N
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q06106 887 101101 Q442 K N M P L K K Q K E L K R K A
Red Bread Mold Neurospora crassa Q7SG09 827 90390 A382 R I V H I L P A A A K R E N K
Conservation
Percent
Protein Identity: 100 99.2 93 69.4 N.A. 81.6 N.A. N.A. N.A. 67.7 22.1 61 N.A. 39.9 43.5 34.5 N.A.
Protein Similarity: 100 99.4 93.7 73.4 N.A. 87.8 N.A. N.A. N.A. 79.7 36.5 74.4 N.A. 60.7 58.8 51.8 N.A.
P-Site Identity: 100 100 100 46.6 N.A. 46.6 N.A. N.A. N.A. 66.6 26.6 6.6 N.A. 33.3 6.6 13.3 N.A.
P-Site Similarity: 100 100 100 60 N.A. 53.3 N.A. N.A. N.A. 73.3 53.3 20 N.A. 53.3 26.6 26.6 N.A.
Percent
Protein Identity: 32.4 N.A. N.A. N.A. 29.2 31.2
Protein Similarity: 51.6 N.A. N.A. N.A. 47.4 49.7
P-Site Identity: 0 N.A. N.A. N.A. 13.3 13.3
P-Site Similarity: 13.3 N.A. N.A. N.A. 33.3 46.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 22 8 29 15 8 15 8 15 8 0 0 0 15 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 22 36 22 8 8 15 0 0 0 0 0 0 0 0 8 % D
% Glu: 29 8 15 15 8 8 8 0 0 8 0 0 15 0 8 % E
% Phe: 0 8 0 0 0 0 0 0 0 0 8 0 0 0 0 % F
% Gly: 0 8 0 8 0 0 29 22 0 0 0 0 0 0 0 % G
% His: 0 0 0 15 0 0 0 8 0 0 8 0 0 0 0 % H
% Ile: 8 8 8 8 8 0 0 0 0 0 0 8 0 0 0 % I
% Lys: 8 0 0 0 0 8 8 0 15 0 22 65 58 58 65 % K
% Leu: 0 15 8 0 22 29 8 0 15 8 8 8 15 8 0 % L
% Met: 0 0 8 0 0 8 0 0 8 8 0 0 0 0 0 % M
% Asn: 0 8 0 0 15 0 0 0 0 8 0 0 0 8 8 % N
% Pro: 0 0 0 8 0 0 22 0 0 0 0 0 0 8 0 % P
% Gln: 0 8 8 0 0 8 22 8 0 8 0 0 0 8 0 % Q
% Arg: 15 0 0 0 8 0 0 15 0 0 0 15 15 0 0 % R
% Ser: 15 0 8 22 0 0 0 36 50 50 0 8 0 15 0 % S
% Thr: 8 0 0 15 0 8 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 8 0 8 8 0 0 8 0 8 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 43 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _