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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM21C
All Species:
10.61
Human Site:
S426
Identified Species:
29.17
UniProt:
Q9Y4E1
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y4E1
NP_056077.1
1318
144668
S426
F
G
A
A
S
V
P
S
L
K
E
P
Q
K
P
Chimpanzee
Pan troglodytes
XP_001140122
1427
155633
S514
F
G
A
A
S
V
P
S
L
K
E
P
Q
K
P
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_534948
1205
132612
E360
E
E
D
I
E
D
T
E
E
N
T
R
P
K
K
Cat
Felis silvestris
Mouse
Mus musculus
Q6PGL7
1334
145292
S417
S
G
S
T
S
A
P
S
L
K
E
L
Q
K
H
Rat
Rattus norvegicus
Q80X08
1328
145131
S416
S
G
S
T
S
A
P
S
L
K
E
F
Q
K
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001234527
1326
146323
V418
V
F
S
S
S
V
I
V
E
K
D
K
K
P
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001039320
401
44860
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
A1ZBW7
1469
160880
L510
A
K
P
P
E
Q
K
L
L
S
K
P
K
P
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_800027
2367
254413
L540
G
G
E
D
A
S
D
L
F
G
G
E
N
K
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90
N.A.
66.3
N.A.
72.7
71.3
N.A.
N.A.
54.9
N.A.
22
N.A.
21.2
N.A.
N.A.
23.8
Protein Similarity:
100
90.6
N.A.
71.6
N.A.
79.3
78.8
N.A.
N.A.
68.2
N.A.
26.6
N.A.
38
N.A.
N.A.
35.9
P-Site Identity:
100
100
N.A.
6.6
N.A.
60
60
N.A.
N.A.
20
N.A.
0
N.A.
13.3
N.A.
N.A.
20
P-Site Similarity:
100
100
N.A.
6.6
N.A.
66.6
66.6
N.A.
N.A.
46.6
N.A.
0
N.A.
26.6
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
23
23
12
23
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
12
12
0
12
12
0
0
0
12
0
0
0
0
% D
% Glu:
12
12
12
0
23
0
0
12
23
0
45
12
0
0
0
% E
% Phe:
23
12
0
0
0
0
0
0
12
0
0
12
0
0
0
% F
% Gly:
12
56
0
0
0
0
0
0
0
12
12
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
23
% H
% Ile:
0
0
0
12
0
0
12
0
0
0
0
0
0
0
0
% I
% Lys:
0
12
0
0
0
0
12
0
0
56
12
12
23
67
12
% K
% Leu:
0
0
0
0
0
0
0
23
56
0
0
12
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
12
0
0
12
0
0
% N
% Pro:
0
0
12
12
0
0
45
0
0
0
0
34
12
23
34
% P
% Gln:
0
0
0
0
0
12
0
0
0
0
0
0
45
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% R
% Ser:
23
0
34
12
56
12
0
45
0
12
0
0
0
0
23
% S
% Thr:
0
0
0
23
0
0
12
0
0
0
12
0
0
0
0
% T
% Val:
12
0
0
0
0
34
0
12
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _