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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDR7
All Species:
44.24
Human Site:
S546
Identified Species:
81.11
UniProt:
Q9Y4E6
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y4E6
NP_056100.2
1490
163810
S546
D
H
S
V
G
L
L
S
L
R
E
K
K
C
I
Chimpanzee
Pan troglodytes
XP_523934
1490
163873
S546
D
H
S
V
G
L
L
S
L
R
E
K
K
C
I
Rhesus Macaque
Macaca mulatta
XP_001084761
1490
163815
S546
D
H
S
V
G
L
L
S
L
R
E
K
K
C
I
Dog
Lupus familis
XP_533395
1491
164172
S547
D
H
S
V
G
L
L
S
L
R
E
K
K
C
I
Cat
Felis silvestris
Mouse
Mus musculus
Q920I9
1489
163386
S546
D
H
S
V
G
L
L
S
L
R
E
K
K
C
I
Rat
Rattus norvegicus
Q9ERH3
1488
163172
S546
D
H
S
V
G
L
L
S
L
R
E
K
K
C
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510427
1487
163542
S546
D
H
S
V
G
L
L
S
L
R
E
K
K
C
I
Chicken
Gallus gallus
XP_001231557
1487
163610
S546
D
H
S
V
G
L
L
S
L
R
E
K
K
C
I
Frog
Xenopus laevis
NP_001085633
956
105584
P136
L
L
C
H
G
H
Y
P
E
V
L
V
M
D
A
Zebra Danio
Brachydanio rerio
XP_701317
1059
116678
R239
V
V
C
S
K
Y
W
R
V
F
D
A
G
D
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_569960
1525
168458
S543
D
H
S
V
T
L
V
S
L
Q
E
R
K
C
V
Honey Bee
Apis mellifera
XP_395749
1488
164925
S547
D
H
S
V
T
L
L
S
L
A
E
R
K
C
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784047
1449
158495
S551
D
H
S
V
A
L
L
S
L
R
D
R
K
C
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
99.2
96.9
N.A.
94.9
94.5
N.A.
93.3
90.4
55.7
57.3
N.A.
41.9
45.5
N.A.
47.2
Protein Similarity:
100
99.7
99.7
98.4
N.A.
97.3
97.1
N.A.
96.4
95.3
60.4
64.3
N.A.
61.6
65.2
N.A.
66.1
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
100
6.6
0
N.A.
66.6
73.3
N.A.
73.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
6.6
13.3
N.A.
93.3
86.6
N.A.
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
0
0
0
8
0
8
0
0
8
% A
% Cys:
0
0
16
0
0
0
0
0
0
0
0
0
0
85
0
% C
% Asp:
85
0
0
0
0
0
0
0
0
0
16
0
0
16
0
% D
% Glu:
0
0
0
0
0
0
0
0
8
0
77
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
8
% F
% Gly:
0
0
0
0
70
0
0
0
0
0
0
0
8
0
0
% G
% His:
0
85
0
8
0
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
62
% I
% Lys:
0
0
0
0
8
0
0
0
0
0
0
62
85
0
0
% K
% Leu:
8
8
0
0
0
85
77
0
85
0
8
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
8
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
8
0
70
0
24
0
0
0
% R
% Ser:
0
0
85
8
0
0
0
85
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
16
0
0
0
0
0
0
0
0
0
0
% T
% Val:
8
8
0
85
0
0
8
0
8
8
0
8
0
0
16
% V
% Trp:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _