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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RAPGEF2
All Species:
26.06
Human Site:
T644
Identified Species:
81.9
UniProt:
Q9Y4G8
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y4G8
NP_055062.1
1499
167417
T644
A
I
R
E
F
A
V
T
A
T
P
D
Q
Y
S
Chimpanzee
Pan troglodytes
XP_001147382
1487
166169
T632
A
I
R
E
F
A
V
T
A
T
P
D
Q
Y
S
Rhesus Macaque
Macaca mulatta
XP_001093090
1662
186468
T790
A
I
R
E
F
A
V
T
A
T
P
D
Q
Y
S
Dog
Lupus familis
XP_853804
1486
166072
T632
A
I
R
E
F
A
V
T
A
T
P
D
Q
Y
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8CHG7
1138
126080
R320
Q
L
S
K
L
A
D
R
I
Q
L
S
G
R
Y
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510215
1657
186069
T806
A
I
R
E
F
A
V
T
A
T
P
D
Q
Y
S
Chicken
Gallus gallus
XP_420387
1661
185877
T826
A
I
R
E
F
A
L
T
A
T
P
D
A
Y
S
Frog
Xenopus laevis
NP_001087405
1420
158654
T572
A
I
R
E
F
A
L
T
A
V
A
D
A
Y
S
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
88.9
97.3
N.A.
71.1
N.A.
N.A.
85.2
81.5
83.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.1
89.4
98
N.A.
72.8
N.A.
N.A.
87.2
84.2
88.8
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
6.6
N.A.
N.A.
100
86.6
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
20
N.A.
N.A.
100
93.3
80
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
88
0
0
0
0
100
0
0
88
0
13
0
25
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
13
0
0
0
0
88
0
0
0
% D
% Glu:
0
0
0
88
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
88
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
13
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
88
0
0
0
0
0
0
13
0
0
0
0
0
0
% I
% Lys:
0
0
0
13
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
13
0
0
13
0
25
0
0
0
13
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
75
0
0
0
0
% P
% Gln:
13
0
0
0
0
0
0
0
0
13
0
0
63
0
0
% Q
% Arg:
0
0
88
0
0
0
0
13
0
0
0
0
0
13
0
% R
% Ser:
0
0
13
0
0
0
0
0
0
0
0
13
0
0
88
% S
% Thr:
0
0
0
0
0
0
0
88
0
75
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
63
0
0
13
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
88
13
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _