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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MYO5A
All Species:
39.39
Human Site:
Y477
Identified Species:
86.67
UniProt:
Q9Y4I1
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y4I1
NP_000250.3
1855
215421
Y477
F
K
L
E
Q
E
E
Y
M
K
E
Q
I
P
W
Chimpanzee
Pan troglodytes
XP_001170385
1855
215257
Y477
F
K
L
E
Q
E
E
Y
M
K
E
Q
I
P
W
Rhesus Macaque
Macaca mulatta
XP_001084476
1835
212895
Y477
F
K
L
E
Q
E
E
Y
M
K
E
Q
I
P
W
Dog
Lupus familis
XP_535487
1930
223940
Y554
F
K
L
E
Q
E
E
Y
M
K
E
Q
I
P
W
Cat
Felis silvestris
Mouse
Mus musculus
Q99104
1853
215577
Y477
F
K
L
E
Q
E
E
Y
M
K
E
Q
I
P
W
Rat
Rattus norvegicus
Q9QYF3
1828
211745
Y477
F
K
L
E
Q
E
E
Y
M
K
E
Q
I
P
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q02440
1829
212364
Y477
F
K
L
E
Q
E
E
Y
M
K
E
Q
I
P
W
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001074428
1844
213173
Y499
F
K
L
E
Q
E
E
Y
M
K
E
Q
I
P
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3Z6
2167
250290
Y471
F
K
L
E
Q
E
E
Y
N
H
E
A
I
N
W
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_999655
1824
211646
Y476
F
K
L
E
Q
E
E
Y
V
K
E
Q
I
E
W
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P19524
1574
180662
L321
Y
K
I
T
V
D
A
L
T
L
V
G
I
T
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
98
90.3
N.A.
92.9
95
N.A.
N.A.
90.5
N.A.
78.3
N.A.
26.3
N.A.
N.A.
51.3
Protein Similarity:
100
99.9
98.4
92.1
N.A.
95.6
96.9
N.A.
N.A.
94.7
N.A.
87.3
N.A.
44.5
N.A.
N.A.
68.8
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
N.A.
100
N.A.
73.3
N.A.
N.A.
86.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
N.A.
100
N.A.
73.3
N.A.
N.A.
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
52
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
10
0
0
0
0
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
91
0
91
91
0
0
0
91
0
0
10
0
% E
% Phe:
91
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% H
% Ile:
0
0
10
0
0
0
0
0
0
0
0
0
100
0
0
% I
% Lys:
0
100
0
0
0
0
0
0
0
82
0
0
0
0
10
% K
% Leu:
0
0
91
0
0
0
0
10
0
10
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
73
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
10
0
0
0
0
10
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
73
0
% P
% Gln:
0
0
0
0
91
0
0
0
0
0
0
82
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
10
0
0
0
0
10
0
0
0
0
10
0
% T
% Val:
0
0
0
0
10
0
0
0
10
0
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
91
% W
% Tyr:
10
0
0
0
0
0
0
91
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _