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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MTL5
All Species:
13.33
Human Site:
S436
Identified Species:
32.59
UniProt:
Q9Y4I5
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y4I5
NP_001034745.1
508
55025
S436
Y
L
P
P
T
K
F
S
G
L
P
R
F
S
H
Chimpanzee
Pan troglodytes
XP_001154282
427
46655
G356
L
P
P
T
K
F
S
G
L
P
R
F
S
H
D
Rhesus Macaque
Macaca mulatta
XP_001102124
508
55078
S436
H
L
P
P
T
K
F
S
G
L
P
K
F
S
Q
Dog
Lupus familis
XP_854573
586
64510
S514
H
L
S
P
T
K
F
S
G
L
P
K
F
R
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9WTJ6
475
50598
S403
Y
L
S
P
A
K
F
S
G
P
P
K
L
R
K
Rat
Rattus norvegicus
Q5XHX9
475
50450
S403
H
L
S
P
A
K
F
S
G
P
P
R
L
R
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001231493
503
55627
E436
L
F
L
T
S
T
F
E
I
S
P
K
L
E
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q08CM4
771
81370
Q688
A
K
T
K
L
S
S
Q
I
S
D
L
L
T
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
A1Z9E2
950
100003
N880
K
N
K
Q
L
N
E
N
R
A
N
I
Y
F
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792482
689
72067
Q565
A
R
T
K
L
S
S
Q
L
Q
D
Y
P
T
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74.2
93.6
70.9
N.A.
64.5
63.7
N.A.
N.A.
45
N.A.
28.5
N.A.
22.7
N.A.
N.A.
26.4
Protein Similarity:
100
76.5
96.4
76.1
N.A.
74.4
73.6
N.A.
N.A.
60.8
N.A.
41.7
N.A.
34.4
N.A.
N.A.
42.2
P-Site Identity:
100
6.6
80
66.6
N.A.
53.3
53.3
N.A.
N.A.
13.3
N.A.
0
N.A.
0
N.A.
N.A.
0
P-Site Similarity:
100
6.6
93.3
80
N.A.
60
60
N.A.
N.A.
26.6
N.A.
6.6
N.A.
13.3
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
0
0
0
20
0
0
0
0
10
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
20
0
0
0
10
% D
% Glu:
0
0
0
0
0
0
10
10
0
0
0
0
0
10
0
% E
% Phe:
0
10
0
0
0
10
60
0
0
0
0
10
30
10
0
% F
% Gly:
0
0
0
0
0
0
0
10
50
0
0
0
0
0
0
% G
% His:
30
0
0
0
0
0
0
0
0
0
0
0
0
10
10
% H
% Ile:
0
0
0
0
0
0
0
0
20
0
0
10
0
0
0
% I
% Lys:
10
10
10
20
10
50
0
0
0
0
0
40
0
0
50
% K
% Leu:
20
50
10
0
30
0
0
0
20
30
0
10
40
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
0
10
0
10
0
0
10
0
0
0
0
% N
% Pro:
0
10
30
50
0
0
0
0
0
30
60
0
10
0
0
% P
% Gln:
0
0
0
10
0
0
0
20
0
10
0
0
0
0
10
% Q
% Arg:
0
10
0
0
0
0
0
0
10
0
10
20
0
30
10
% R
% Ser:
0
0
30
0
10
20
30
50
0
20
0
0
10
20
0
% S
% Thr:
0
0
20
20
30
10
0
0
0
0
0
0
0
20
10
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
20
0
0
0
0
0
0
0
0
0
0
10
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _