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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MTL5
All Species:
9.7
Human Site:
S448
Identified Species:
23.7
UniProt:
Q9Y4I5
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y4I5
NP_001034745.1
508
55025
S448
F
S
H
D
R
R
P
S
S
C
I
S
W
E
V
Chimpanzee
Pan troglodytes
XP_001154282
427
46655
S368
S
H
D
R
R
P
S
S
C
I
S
W
E
V
V
Rhesus Macaque
Macaca mulatta
XP_001102124
508
55078
S448
F
S
Q
D
R
R
P
S
S
C
I
S
W
E
V
Dog
Lupus familis
XP_854573
586
64510
S526
F
R
K
D
R
Q
S
S
S
C
I
S
W
E
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9WTJ6
475
50598
F415
L
R
K
N
R
Q
A
F
S
C
I
S
W
E
V
Rat
Rattus norvegicus
Q5XHX9
475
50450
F415
L
R
K
N
R
Q
A
F
S
C
I
S
W
E
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001231493
503
55627
A448
L
E
K
D
R
E
T
A
V
S
I
S
W
E
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q08CM4
771
81370
I700
L
T
R
T
T
P
A
I
T
S
G
G
G
K
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
A1Z9E2
950
100003
E892
Y
F
T
D
D
V
I
E
A
T
I
M
C
M
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792482
689
72067
S577
P
T
K
T
R
E
F
S
D
T
G
E
R
L
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74.2
93.6
70.9
N.A.
64.5
63.7
N.A.
N.A.
45
N.A.
28.5
N.A.
22.7
N.A.
N.A.
26.4
Protein Similarity:
100
76.5
96.4
76.1
N.A.
74.4
73.6
N.A.
N.A.
60.8
N.A.
41.7
N.A.
34.4
N.A.
N.A.
42.2
P-Site Identity:
100
20
93.3
73.3
N.A.
53.3
53.3
N.A.
N.A.
40
N.A.
0
N.A.
13.3
N.A.
N.A.
13.3
P-Site Similarity:
100
20
93.3
80
N.A.
66.6
66.6
N.A.
N.A.
46.6
N.A.
26.6
N.A.
33.3
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
30
10
10
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
10
50
0
0
10
0
0
% C
% Asp:
0
0
10
50
10
0
0
0
10
0
0
0
0
0
10
% D
% Glu:
0
10
0
0
0
20
0
10
0
0
0
10
10
60
0
% E
% Phe:
30
10
0
0
0
0
10
20
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
20
10
10
0
0
% G
% His:
0
10
10
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
10
10
0
10
70
0
0
0
10
% I
% Lys:
0
0
50
0
0
0
0
0
0
0
0
0
0
10
0
% K
% Leu:
40
0
0
0
0
0
0
0
0
0
0
0
0
10
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
10
0
10
0
% M
% Asn:
0
0
0
20
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
10
0
0
0
0
20
20
0
0
0
0
0
0
0
10
% P
% Gln:
0
0
10
0
0
30
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
30
10
10
80
20
0
0
0
0
0
0
10
0
0
% R
% Ser:
10
20
0
0
0
0
20
50
50
20
10
60
0
0
0
% S
% Thr:
0
20
10
20
10
0
10
0
10
20
0
0
0
0
0
% T
% Val:
0
0
0
0
0
10
0
0
10
0
0
0
0
10
60
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
10
60
0
0
% W
% Tyr:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _