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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MTL5
All Species:
14.85
Human Site:
T166
Identified Species:
36.3
UniProt:
Q9Y4I5
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y4I5
NP_001034745.1
508
55025
T166
E
I
K
E
A
G
G
T
T
T
S
N
N
P
E
Chimpanzee
Pan troglodytes
XP_001154282
427
46655
Q133
S
N
P
M
V
I
C
Q
L
K
G
G
T
Q
M
Rhesus Macaque
Macaca mulatta
XP_001102124
508
55078
T166
E
I
K
E
A
G
G
T
I
T
S
N
N
P
E
Dog
Lupus familis
XP_854573
586
64510
T243
E
I
K
E
A
G
G
T
I
I
S
N
N
P
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9WTJ6
475
50598
S137
E
I
K
E
A
G
G
S
V
P
G
G
S
P
E
Rat
Rattus norvegicus
Q5XHX9
475
50450
G137
E
I
K
E
A
G
G
G
V
P
G
S
S
P
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001231493
503
55627
N167
E
V
R
D
A
I
R
N
V
T
E
S
H
E
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q08CM4
771
81370
T394
V
R
L
V
T
A
T
T
G
S
S
T
V
Q
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
A1Z9E2
950
100003
S592
R
V
V
S
S
S
T
S
P
S
S
N
S
T
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792482
689
72067
I325
Q
L
A
N
A
K
P
I
A
P
A
P
A
L
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74.2
93.6
70.9
N.A.
64.5
63.7
N.A.
N.A.
45
N.A.
28.5
N.A.
22.7
N.A.
N.A.
26.4
Protein Similarity:
100
76.5
96.4
76.1
N.A.
74.4
73.6
N.A.
N.A.
60.8
N.A.
41.7
N.A.
34.4
N.A.
N.A.
42.2
P-Site Identity:
100
0
93.3
86.6
N.A.
60
60
N.A.
N.A.
20
N.A.
13.3
N.A.
13.3
N.A.
N.A.
6.6
P-Site Similarity:
100
0
93.3
86.6
N.A.
73.3
73.3
N.A.
N.A.
60
N.A.
20
N.A.
53.3
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
70
10
0
0
10
0
10
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
10
% D
% Glu:
60
0
0
50
0
0
0
0
0
0
10
0
0
10
50
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
50
50
10
10
0
30
20
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% H
% Ile:
0
50
0
0
0
20
0
10
20
10
0
0
0
0
0
% I
% Lys:
0
0
50
0
0
10
0
0
0
10
0
0
0
0
10
% K
% Leu:
0
10
10
0
0
0
0
0
10
0
0
0
0
10
0
% L
% Met:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
0
10
0
10
0
0
0
10
0
0
0
40
30
0
0
% N
% Pro:
0
0
10
0
0
0
10
0
10
30
0
10
0
50
0
% P
% Gln:
10
0
0
0
0
0
0
10
0
0
0
0
0
20
0
% Q
% Arg:
10
10
10
0
0
0
10
0
0
0
0
0
0
0
0
% R
% Ser:
10
0
0
10
10
10
0
20
0
20
50
20
30
0
0
% S
% Thr:
0
0
0
0
10
0
20
40
10
30
0
10
10
10
10
% T
% Val:
10
20
10
10
10
0
0
0
30
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _