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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MTL5
All Species:
22.12
Human Site:
Y403
Identified Species:
54.07
UniProt:
Q9Y4I5
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y4I5
NP_001034745.1
508
55025
Y403
K
C
I
G
C
K
N
Y
E
E
S
P
E
R
K
Chimpanzee
Pan troglodytes
XP_001154282
427
46655
E323
C
I
G
C
E
N
C
E
E
S
P
E
R
K
T
Rhesus Macaque
Macaca mulatta
XP_001102124
508
55078
Y403
K
C
I
G
C
K
N
Y
E
E
S
P
E
R
K
Dog
Lupus familis
XP_854573
586
64510
Y481
K
C
I
G
C
K
N
Y
E
E
S
P
E
Q
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9WTJ6
475
50598
Y370
K
C
I
A
C
K
N
Y
E
E
S
P
E
R
K
Rat
Rattus norvegicus
Q5XHX9
475
50450
Y370
K
C
I
A
C
K
N
Y
E
E
S
P
E
R
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001231493
503
55627
Y403
K
C
I
G
C
K
N
Y
E
E
S
P
D
K
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q08CM4
771
81370
F655
K
C
M
G
C
K
N
F
E
E
S
P
E
R
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
A1Z9E2
950
100003
M847
K
C
V
G
C
R
N
M
E
D
R
P
D
V
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792482
689
72067
F532
K
C
V
G
C
K
N
F
E
E
S
P
E
R
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74.2
93.6
70.9
N.A.
64.5
63.7
N.A.
N.A.
45
N.A.
28.5
N.A.
22.7
N.A.
N.A.
26.4
Protein Similarity:
100
76.5
96.4
76.1
N.A.
74.4
73.6
N.A.
N.A.
60.8
N.A.
41.7
N.A.
34.4
N.A.
N.A.
42.2
P-Site Identity:
100
6.6
100
93.3
N.A.
93.3
93.3
N.A.
N.A.
86.6
N.A.
86.6
N.A.
46.6
N.A.
N.A.
86.6
P-Site Similarity:
100
13.3
100
100
N.A.
93.3
93.3
N.A.
N.A.
100
N.A.
100
N.A.
73.3
N.A.
N.A.
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
20
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
10
90
0
10
90
0
10
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
10
0
0
20
0
10
% D
% Glu:
0
0
0
0
10
0
0
10
100
80
0
10
70
0
0
% E
% Phe:
0
0
0
0
0
0
0
20
0
0
0
0
0
0
0
% F
% Gly:
0
0
10
70
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
60
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
90
0
0
0
0
80
0
0
0
0
0
0
0
20
80
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
10
0
0
0
0
10
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
10
90
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
10
90
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% Q
% Arg:
0
0
0
0
0
10
0
0
0
0
10
0
10
60
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
10
80
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% T
% Val:
0
0
20
0
0
0
0
0
0
0
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
60
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _