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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MTL5
All Species:
16.67
Human Site:
Y418
Identified Species:
40.74
UniProt:
Q9Y4I5
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y4I5
NP_001034745.1
508
55025
Y418
T
L
M
S
M
P
N
Y
M
Q
T
G
G
L
E
Chimpanzee
Pan troglodytes
XP_001154282
427
46655
M338
L
M
S
V
P
N
Y
M
Q
T
G
G
L
E
G
Rhesus Macaque
Macaca mulatta
XP_001102124
508
55078
Y418
T
L
M
S
M
P
N
Y
V
Q
A
G
G
L
E
Dog
Lupus familis
XP_854573
586
64510
Y496
T
L
M
N
M
P
N
Y
M
E
I
G
G
F
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9WTJ6
475
50598
Y385
M
L
M
S
T
P
H
Y
M
E
P
G
D
F
E
Rat
Rattus norvegicus
Q5XHX9
475
50450
Y385
M
L
M
S
T
P
H
Y
M
E
P
G
D
F
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001231493
503
55627
Y418
T
Q
P
T
M
L
N
Y
M
D
I
G
N
N
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q08CM4
771
81370
A670
T
L
M
H
L
A
D
A
A
E
V
R
V
Q
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
A1Z9E2
950
100003
M862
M
D
S
L
D
G
L
M
G
V
E
G
Q
K
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792482
689
72067
A547
T
L
M
H
L
A
D
A
A
E
V
R
V
Q
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74.2
93.6
70.9
N.A.
64.5
63.7
N.A.
N.A.
45
N.A.
28.5
N.A.
22.7
N.A.
N.A.
26.4
Protein Similarity:
100
76.5
96.4
76.1
N.A.
74.4
73.6
N.A.
N.A.
60.8
N.A.
41.7
N.A.
34.4
N.A.
N.A.
42.2
P-Site Identity:
100
6.6
86.6
73.3
N.A.
53.3
53.3
N.A.
N.A.
40
N.A.
20
N.A.
6.6
N.A.
N.A.
20
P-Site Similarity:
100
13.3
93.3
86.6
N.A.
66.6
66.6
N.A.
N.A.
53.3
N.A.
46.6
N.A.
13.3
N.A.
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
20
0
20
20
0
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
10
0
20
0
0
10
0
0
20
0
10
% D
% Glu:
0
0
0
0
0
0
0
0
0
50
10
0
0
10
50
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
30
0
% F
% Gly:
0
0
0
0
0
10
0
0
10
0
10
80
30
0
10
% G
% His:
0
0
0
20
0
0
20
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
20
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
10
% K
% Leu:
10
70
0
10
20
10
10
0
0
0
0
0
10
20
0
% L
% Met:
30
10
70
0
40
0
0
20
50
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
10
40
0
0
0
0
0
10
10
0
% N
% Pro:
0
0
10
0
10
50
0
0
0
0
20
0
0
0
0
% P
% Gln:
0
10
0
0
0
0
0
0
10
20
0
0
10
20
20
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
20
0
0
0
% R
% Ser:
0
0
20
40
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
60
0
0
10
20
0
0
0
0
10
10
0
0
0
0
% T
% Val:
0
0
0
10
0
0
0
0
10
10
20
0
20
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
10
60
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _