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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AIM1
All Species:
4.55
Human Site:
T246
Identified Species:
20
UniProt:
Q9Y4K1
Number Species:
5
Phosphosite Substitution
Charge Score:
-0.4
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y4K1
NP_001615.1
1723
188676
T246
H
V
E
L
N
L
K
T
P
K
N
L
D
S
L
Chimpanzee
Pan troglodytes
XP_518660
2136
232421
T654
H
V
E
L
N
L
K
T
P
K
N
L
D
S
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_532248
1656
179895
R229
I
S
L
F
E
N
K
R
A
N
S
S
S
P
R
Cat
Felis silvestris
Mouse
Mus musculus
Q80W49
1005
114243
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512115
1491
160793
R68
S
P
R
H
A
D
T
R
G
P
K
G
A
A
P
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_684861
2843
312344
I390
H
L
T
P
T
N
T
I
P
P
Q
A
Q
E
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
79.6
N.A.
68.2
N.A.
24
N.A.
N.A.
51.4
N.A.
N.A.
26.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
80
N.A.
75.8
N.A.
35.9
N.A.
N.A.
62.7
N.A.
N.A.
40
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
N.A.
6.6
N.A.
0
N.A.
N.A.
0
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
13.3
N.A.
0
N.A.
N.A.
6.6
N.A.
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
17
0
0
0
17
0
0
17
17
17
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
17
0
0
0
0
0
0
34
0
0
% D
% Glu:
0
0
34
0
17
0
0
0
0
0
0
0
0
17
0
% E
% Phe:
0
0
0
17
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
17
0
0
17
0
0
0
% G
% His:
50
0
0
17
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
17
0
0
0
0
0
0
17
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
50
0
0
34
17
0
0
0
0
% K
% Leu:
0
17
17
34
0
34
0
0
0
0
0
34
0
0
34
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
34
34
0
0
0
17
34
0
0
0
0
% N
% Pro:
0
17
0
17
0
0
0
0
50
34
0
0
0
17
17
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
17
0
17
0
0
% Q
% Arg:
0
0
17
0
0
0
0
34
0
0
0
0
0
0
34
% R
% Ser:
17
17
0
0
0
0
0
0
0
0
17
17
17
34
0
% S
% Thr:
0
0
17
0
17
0
34
34
0
0
0
0
0
0
0
% T
% Val:
0
34
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _