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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TRAF6 All Species: 17.27
Human Site: S12 Identified Species: 38
UniProt: Q9Y4K3 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.3
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y4K3 NP_004611.1 522 59573 S12 N C E N S C G S S Q S E S D C
Chimpanzee Pan troglodytes XP_001154065 522 59541 S12 N C E N S C G S S Q S E S D C
Rhesus Macaque Macaca mulatta B6CJY5 522 59446 S12 N C E N S C G S S Q S E S D C
Dog Lupus familis XP_857114 509 56866 C34 K P E D K Y L C S A C R N V L
Cat Felis silvestris
Mouse Mus musculus P70196 530 60051 S12 N C E N S C G S S Q S S S D C
Rat Rattus norvegicus B5DF45 530 60235 S12 N C E N S C A S S Q S S S D C
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509071 544 61760 A12 N C E N S C G A S Q S E G D C
Chicken Gallus gallus XP_421089 524 59597 G12 H S D S S C G G R D L D S G C
Frog Xenopus laevis Q3MV19 556 63019 D14 R T S L E A G D S E D A C C A
Zebra Danio Brachydanio rerio Q6IWL4 542 61788 D13 V D K S S F D D V C C D S G H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_789994 462 53330 D22 Q A R C P Y Q D C P D L L E L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 98 27.5 N.A. 88.4 87.1 N.A. 81.8 76.1 62.9 57 N.A. N.A. N.A. N.A. 24.3
Protein Similarity: 100 99.8 99.4 45.9 N.A. 93 91.8 N.A. 88.2 86.2 74.4 70.8 N.A. N.A. N.A. N.A. 41
P-Site Identity: 100 100 100 13.3 N.A. 93.3 86.6 N.A. 86.6 33.3 13.3 13.3 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 100 100 26.6 N.A. 93.3 86.6 N.A. 93.3 60 20 33.3 N.A. N.A. N.A. N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 0 0 10 10 10 0 10 0 10 0 0 10 % A
% Cys: 0 55 0 10 0 64 0 10 10 10 19 0 10 10 64 % C
% Asp: 0 10 10 10 0 0 10 28 0 10 19 19 0 55 0 % D
% Glu: 0 0 64 0 10 0 0 0 0 10 0 37 0 10 0 % E
% Phe: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 64 10 0 0 0 0 10 19 0 % G
% His: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 10 0 10 0 10 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 10 0 0 10 0 0 0 10 10 10 0 19 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 55 0 0 55 0 0 0 0 0 0 0 0 10 0 0 % N
% Pro: 0 10 0 0 10 0 0 0 0 10 0 0 0 0 0 % P
% Gln: 10 0 0 0 0 0 10 0 0 55 0 0 0 0 0 % Q
% Arg: 10 0 10 0 0 0 0 0 10 0 0 10 0 0 0 % R
% Ser: 0 10 10 19 73 0 0 46 73 0 55 19 64 0 0 % S
% Thr: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 10 0 0 0 0 0 0 0 10 0 0 0 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 19 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _