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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TRAF6
All Species:
9.39
Human Site:
S290
Identified Species:
20.67
UniProt:
Q9Y4K3
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y4K3
NP_004611.1
522
59573
S290
I
P
D
S
G
Y
I
S
E
V
R
N
F
Q
E
Chimpanzee
Pan troglodytes
XP_001154065
522
59541
S290
I
P
D
S
G
Y
I
S
E
V
R
N
F
Q
E
Rhesus Macaque
Macaca mulatta
B6CJY5
522
59446
S290
I
P
D
S
G
Y
V
S
E
V
R
N
F
Q
E
Dog
Lupus familis
XP_857114
509
56866
A268
A
S
T
L
H
P
E
A
E
L
S
K
A
A
E
Cat
Felis silvestris
Mouse
Mus musculus
P70196
530
60051
A290
A
L
R
P
C
D
A
A
S
P
S
R
G
C
R
Rat
Rattus norvegicus
B5DF45
530
60235
S290
S
L
R
P
C
D
A
S
S
P
S
R
G
C
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509071
544
61760
Q290
T
A
L
T
P
V
P
Q
L
D
V
L
P
F
D
Chicken
Gallus gallus
XP_421089
524
59597
F290
T
A
T
N
P
V
P
F
I
N
E
V
E
N
F
Frog
Xenopus laevis
Q3MV19
556
63019
D292
T
P
T
S
H
I
S
D
I
S
F
C
D
P
N
Zebra Danio
Brachydanio rerio
Q6IWL4
542
61788
A291
N
N
C
T
M
P
S
A
A
A
H
L
S
S
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789994
462
53330
D246
S
G
A
F
D
P
M
D
Q
F
R
A
L
R
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98
27.5
N.A.
88.4
87.1
N.A.
81.8
76.1
62.9
57
N.A.
N.A.
N.A.
N.A.
24.3
Protein Similarity:
100
99.8
99.4
45.9
N.A.
93
91.8
N.A.
88.2
86.2
74.4
70.8
N.A.
N.A.
N.A.
N.A.
41
P-Site Identity:
100
100
93.3
13.3
N.A.
0
6.6
N.A.
0
0
13.3
0
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
26.6
N.A.
6.6
6.6
N.A.
13.3
6.6
13.3
20
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
19
10
0
0
0
19
28
10
10
0
10
10
10
0
% A
% Cys:
0
0
10
0
19
0
0
0
0
0
0
10
0
19
0
% C
% Asp:
0
0
28
0
10
19
0
19
0
10
0
0
10
0
19
% D
% Glu:
0
0
0
0
0
0
10
0
37
0
10
0
10
0
37
% E
% Phe:
0
0
0
10
0
0
0
10
0
10
10
0
28
10
10
% F
% Gly:
0
10
0
0
28
0
0
0
0
0
0
0
19
0
0
% G
% His:
0
0
0
0
19
0
0
0
0
0
10
0
0
0
0
% H
% Ile:
28
0
0
0
0
10
19
0
19
0
0
0
0
0
10
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% K
% Leu:
0
19
10
10
0
0
0
0
10
10
0
19
10
0
0
% L
% Met:
0
0
0
0
10
0
10
0
0
0
0
0
0
0
0
% M
% Asn:
10
10
0
10
0
0
0
0
0
10
0
28
0
10
10
% N
% Pro:
0
37
0
19
19
28
19
0
0
19
0
0
10
10
0
% P
% Gln:
0
0
0
0
0
0
0
10
10
0
0
0
0
28
0
% Q
% Arg:
0
0
19
0
0
0
0
0
0
0
37
19
0
10
19
% R
% Ser:
19
10
0
37
0
0
19
37
19
10
28
0
10
10
0
% S
% Thr:
28
0
28
19
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
19
10
0
0
28
10
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
28
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _