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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TRAF6 All Species: 28.79
Human Site: S48 Identified Species: 63.33
UniProt: Q9Y4K3 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y4K3 NP_004611.1 522 59573 S48 S T G N L S S S F M E E I Q G
Chimpanzee Pan troglodytes XP_001154065 522 59541 S48 S T G N L S S S F M E E I Q G
Rhesus Macaque Macaca mulatta B6CJY5 522 59446 S48 S T G N L S S S F M E D I Q G
Dog Lupus familis XP_857114 509 56866 A70 S S G P Q N C A A C V H E G I
Cat Felis silvestris
Mouse Mus musculus P70196 530 60051 S48 S T G N L S S S F M E E I Q G
Rat Rattus norvegicus B5DF45 530 60235 S48 S T G N L S S S F M E E I Q G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509071 544 61760 S48 N T G N L H N S F M A E T Q G
Chicken Gallus gallus XP_421089 524 59597 S48 G T G N P P S S F T E E T Q G
Frog Xenopus laevis Q3MV19 556 63019 L50 P S G T T Q N L D V E E I Q G
Zebra Danio Brachydanio rerio Q6IWL4 542 61788 S49 S T I S V S S S M P P D Q Q G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_789994 462 53330 S58 G A S M R R R S I D R H V E K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 98 27.5 N.A. 88.4 87.1 N.A. 81.8 76.1 62.9 57 N.A. N.A. N.A. N.A. 24.3
Protein Similarity: 100 99.8 99.4 45.9 N.A. 93 91.8 N.A. 88.2 86.2 74.4 70.8 N.A. N.A. N.A. N.A. 41
P-Site Identity: 100 100 93.3 13.3 N.A. 100 100 N.A. 66.6 66.6 40 46.6 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 100 33.3 N.A. 100 100 N.A. 80 66.6 60 66.6 N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 0 0 0 0 10 10 0 10 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 10 0 0 10 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 10 10 0 19 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 64 64 10 10 0 % E
% Phe: 0 0 0 0 0 0 0 0 64 0 0 0 0 0 0 % F
% Gly: 19 0 82 0 0 0 0 0 0 0 0 0 0 10 82 % G
% His: 0 0 0 0 0 10 0 0 0 0 0 19 0 0 0 % H
% Ile: 0 0 10 0 0 0 0 0 10 0 0 0 55 0 10 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % K
% Leu: 0 0 0 0 55 0 0 10 0 0 0 0 0 0 0 % L
% Met: 0 0 0 10 0 0 0 0 10 55 0 0 0 0 0 % M
% Asn: 10 0 0 64 0 10 19 0 0 0 0 0 0 0 0 % N
% Pro: 10 0 0 10 10 10 0 0 0 10 10 0 0 0 0 % P
% Gln: 0 0 0 0 10 10 0 0 0 0 0 0 10 82 0 % Q
% Arg: 0 0 0 0 10 10 10 0 0 0 10 0 0 0 0 % R
% Ser: 64 19 10 10 0 55 64 82 0 0 0 0 0 0 0 % S
% Thr: 0 73 0 10 10 0 0 0 0 10 0 0 19 0 0 % T
% Val: 0 0 0 0 10 0 0 0 0 10 10 0 10 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _