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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TRAF6
All Species:
29.02
Human Site:
S517
Identified Species:
63.85
UniProt:
Q9Y4K3
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y4K3
NP_004611.1
522
59573
S517
R
E
G
F
Q
P
R
S
T
D
A
G
V
_
_
Chimpanzee
Pan troglodytes
XP_001154065
522
59541
S517
R
E
G
F
Q
P
R
S
T
D
A
G
V
_
_
Rhesus Macaque
Macaca mulatta
B6CJY5
522
59446
S517
R
E
G
F
Q
P
R
S
T
D
S
G
V
_
_
Dog
Lupus familis
XP_857114
509
56866
R494
E
A
K
N
S
Y
V
R
D
D
A
I
F
I
K
Cat
Felis silvestris
Mouse
Mus musculus
P70196
530
60051
S525
K
E
G
F
Q
P
R
S
T
D
A
G
V
_
_
Rat
Rattus norvegicus
B5DF45
530
60235
S525
K
E
G
F
Q
P
R
S
T
D
A
G
V
_
_
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509071
544
61760
S539
R
E
G
F
Q
P
R
S
T
D
P
G
V
_
_
Chicken
Gallus gallus
XP_421089
524
59597
S519
R
E
G
F
Q
A
R
S
T
D
G
A
A
_
_
Frog
Xenopus laevis
Q3MV19
556
63019
S551
R
E
G
F
Q
P
R
S
G
E
G
T
L
_
_
Zebra Danio
Brachydanio rerio
Q6IWL4
542
61788
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789994
462
53330
K454
K
D
N
T
I
L
I
K
V
E
V
H
P
Q
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98
27.5
N.A.
88.4
87.1
N.A.
81.8
76.1
62.9
57
N.A.
N.A.
N.A.
N.A.
24.3
Protein Similarity:
100
99.8
99.4
45.9
N.A.
93
91.8
N.A.
88.2
86.2
74.4
70.8
N.A.
N.A.
N.A.
N.A.
41
P-Site Identity:
100
100
92.3
13.3
N.A.
92.3
92.3
N.A.
92.3
69.2
61.5
0
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
20
N.A.
100
100
N.A.
92.3
69.2
76.9
0
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
10
0
0
0
0
46
10
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
0
0
0
0
10
73
0
0
0
0
0
% D
% Glu:
10
73
0
0
0
0
0
0
0
19
0
0
0
0
0
% E
% Phe:
0
0
0
73
0
0
0
0
0
0
0
0
10
0
0
% F
% Gly:
0
0
73
0
0
0
0
0
10
0
19
55
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% H
% Ile:
0
0
0
0
10
0
10
0
0
0
0
10
0
10
0
% I
% Lys:
28
0
10
0
0
0
0
10
0
0
0
0
0
0
10
% K
% Leu:
0
0
0
0
0
10
0
0
0
0
0
0
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
10
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
64
0
0
0
0
10
0
10
0
0
% P
% Gln:
0
0
0
0
73
0
0
0
0
0
0
0
0
10
0
% Q
% Arg:
55
0
0
0
0
0
73
10
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
10
0
0
73
0
0
10
0
0
0
10
% S
% Thr:
0
0
0
10
0
0
0
0
64
0
0
10
0
0
0
% T
% Val:
0
0
0
0
0
0
10
0
10
0
10
0
55
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
73
73
% _