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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TRAF6
All Species:
23.33
Human Site:
T486
Identified Species:
51.33
UniProt:
Q9Y4K3
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y4K3
NP_004611.1
522
59573
T486
L
E
A
L
R
Q
R
T
F
I
K
D
D
T
L
Chimpanzee
Pan troglodytes
XP_001154065
522
59541
T486
L
E
A
L
R
Q
R
T
F
I
K
D
D
T
L
Rhesus Macaque
Macaca mulatta
B6CJY5
522
59446
T486
L
E
A
L
R
Q
R
T
F
I
K
D
D
T
L
Dog
Lupus familis
XP_857114
509
56866
S463
R
P
D
V
T
S
S
S
F
Q
R
P
V
S
D
Cat
Felis silvestris
Mouse
Mus musculus
P70196
530
60051
T494
L
E
A
L
R
Q
G
T
F
I
K
D
D
T
L
Rat
Rattus norvegicus
B5DF45
530
60235
T494
L
E
A
L
R
Q
G
T
F
I
K
D
D
T
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509071
544
61760
A508
L
Q
A
L
R
Q
R
A
F
I
K
D
D
T
L
Chicken
Gallus gallus
XP_421089
524
59597
T488
L
Q
T
L
K
Q
R
T
F
V
K
D
D
T
L
Frog
Xenopus laevis
Q3MV19
556
63019
Q520
L
N
T
L
K
Q
R
Q
Y
V
K
N
D
T
L
Zebra Danio
Brachydanio rerio
Q6IWL4
542
61788
G507
L
Q
A
L
R
Q
R
G
F
V
K
E
D
V
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789994
462
53330
R423
F
K
K
P
K
T
A
R
N
H
K
G
F
G
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98
27.5
N.A.
88.4
87.1
N.A.
81.8
76.1
62.9
57
N.A.
N.A.
N.A.
N.A.
24.3
Protein Similarity:
100
99.8
99.4
45.9
N.A.
93
91.8
N.A.
88.2
86.2
74.4
70.8
N.A.
N.A.
N.A.
N.A.
41
P-Site Identity:
100
100
100
6.6
N.A.
93.3
93.3
N.A.
86.6
73.3
53.3
66.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
33.3
N.A.
93.3
93.3
N.A.
93.3
93.3
80
86.6
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
64
0
0
0
10
10
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
0
0
0
0
0
0
0
64
82
0
10
% D
% Glu:
0
46
0
0
0
0
0
0
0
0
0
10
0
0
0
% E
% Phe:
10
0
0
0
0
0
0
0
82
0
0
0
10
0
0
% F
% Gly:
0
0
0
0
0
0
19
10
0
0
0
10
0
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
55
0
0
0
0
0
% I
% Lys:
0
10
10
0
28
0
0
0
0
0
91
0
0
0
0
% K
% Leu:
82
0
0
82
0
0
0
0
0
0
0
0
0
0
82
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
0
0
0
0
10
0
0
10
0
0
0
% N
% Pro:
0
10
0
10
0
0
0
0
0
0
0
10
0
0
0
% P
% Gln:
0
28
0
0
0
82
0
10
0
10
0
0
0
0
0
% Q
% Arg:
10
0
0
0
64
0
64
10
0
0
10
0
0
0
0
% R
% Ser:
0
0
0
0
0
10
10
10
0
0
0
0
0
10
0
% S
% Thr:
0
0
19
0
10
10
0
55
0
0
0
0
0
73
0
% T
% Val:
0
0
0
10
0
0
0
0
0
28
0
0
10
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _