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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HYOU1
All Species:
30.3
Human Site:
S536
Identified Species:
51.28
UniProt:
Q9Y4L1
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y4L1
NP_001124463.1
999
111335
S536
K
K
Y
P
D
Y
E
S
K
G
I
K
A
H
F
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001096142
916
102146
S453
K
K
Y
P
D
Y
E
S
K
G
I
K
A
H
F
Dog
Lupus familis
XP_536547
1100
121754
S536
K
K
Y
P
D
Y
E
S
K
G
I
K
A
H
F
Cat
Felis silvestris
Mouse
Mus musculus
Q9JKR6
999
111163
S536
K
K
Y
P
D
Y
E
S
K
G
I
K
A
H
F
Rat
Rattus norvegicus
Q63617
999
111271
S536
K
K
Y
P
D
Y
E
S
K
G
I
K
A
H
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZLK7
1002
112301
S528
K
K
H
S
D
Y
E
S
K
G
I
K
A
H
F
Frog
Xenopus laevis
Q566I3
646
72655
V254
P
Q
L
Q
I
R
G
V
G
F
D
R
T
L
G
Zebra Danio
Brachydanio rerio
Q7ZUW2
980
110301
S526
K
K
H
S
D
A
E
S
K
G
I
K
A
H
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8INI8
641
70177
K249
E
F
K
R
K
Y
K
K
D
L
R
S
N
P
R
Honey Bee
Apis mellifera
XP_624153
932
105575
S521
H
L
K
D
G
A
E
S
K
G
I
K
A
H
F
Nematode Worm
Caenorhab. elegans
P09446
640
69704
R248
H
F
C
A
E
F
K
R
K
H
K
K
D
L
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002322555
881
98313
I477
S
K
M
F
R
S
I
I
H
T
K
D
F
E
V
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_567510
867
96706
S471
L
P
S
K
M
F
R
S
F
V
L
D
K
D
F
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
O74225
707
78655
V315
V
E
P
L
L
A
K
V
H
V
P
L
E
Q
A
Conservation
Percent
Protein Identity:
100
N.A.
89
83.3
N.A.
92
91.6
N.A.
N.A.
69.1
49.3
65.3
N.A.
24.5
42.4
24.6
N.A.
Protein Similarity:
100
N.A.
90
86
N.A.
95.5
94.7
N.A.
N.A.
80.7
56.4
77.4
N.A.
38.7
60
39.5
N.A.
P-Site Identity:
100
N.A.
100
100
N.A.
100
100
N.A.
N.A.
86.6
0
80
N.A.
6.6
60
13.3
N.A.
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
N.A.
93.3
13.3
86.6
N.A.
20
60
33.3
N.A.
Percent
Protein Identity:
29.7
N.A.
N.A.
30.7
N.A.
26.5
Protein Similarity:
50.7
N.A.
N.A.
49
N.A.
43.1
P-Site Identity:
6.6
N.A.
N.A.
13.3
N.A.
0
P-Site Similarity:
6.6
N.A.
N.A.
26.6
N.A.
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
22
0
0
0
0
0
0
58
0
15
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
50
0
0
0
8
0
8
15
8
8
0
% D
% Glu:
8
8
0
0
8
0
58
0
0
0
0
0
8
8
0
% E
% Phe:
0
15
0
8
0
15
0
0
8
8
0
0
8
0
65
% F
% Gly:
0
0
0
0
8
0
8
0
8
58
0
0
0
0
8
% G
% His:
15
0
15
0
0
0
0
0
15
8
0
0
0
58
0
% H
% Ile:
0
0
0
0
8
0
8
8
0
0
58
0
0
0
0
% I
% Lys:
50
58
15
8
8
0
22
8
65
0
15
65
8
0
0
% K
% Leu:
8
8
8
8
8
0
0
0
0
8
8
8
0
15
0
% L
% Met:
0
0
8
0
8
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% N
% Pro:
8
8
8
36
0
0
0
0
0
0
8
0
0
8
0
% P
% Gln:
0
8
0
8
0
0
0
0
0
0
0
0
0
8
0
% Q
% Arg:
0
0
0
8
8
8
8
8
0
0
8
8
0
0
8
% R
% Ser:
8
0
8
15
0
8
0
65
0
0
0
8
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
8
0
0
8
0
0
% T
% Val:
8
0
0
0
0
0
0
15
0
15
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
36
0
0
50
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _