Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HYOU1 All Species: 15.76
Human Site: S661 Identified Species: 26.67
UniProt: Q9Y4L1 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y4L1 NP_001124463.1 999 111335 S661 E K E N G D K S E A Q K P S E
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001096142 916 102146 S578 E K E N G D K S E A Q K P S E
Dog Lupus familis XP_536547 1100 121754 S661 E K E K E E K S E A Q K P S E
Cat Felis silvestris
Mouse Mus musculus Q9JKR6 999 111163 P661 E K E S G D K P E A Q K P N E
Rat Rattus norvegicus Q63617 999 111271 S661 E K E S G D K S E A Q K P N E
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZLK7 1002 112301 K666 A R D P K E D K E T V N E E E
Frog Xenopus laevis Q566I3 646 72655 G372 I D Q V I L V G G A T R V P K
Zebra Danio Brachydanio rerio Q7ZUW2 980 110301 K672 D M K P K L Q K K S K I S A D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8INI8 641 70177 V367 S I N P D E A V A Y G A A V Q
Honey Bee Apis mellifera XP_624153 932 105575 L641 I K A D E I K L G S Q I L S G
Nematode Worm Caenorhab. elegans P09446 640 69704 P366 E L N K S I N P D E A V A Y G
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002322555 881 98313 G595 D E K S N S D G V T D N T S I
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_567510 867 96706 S591 L Q T D A E N S T A S N T T A
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa O74225 707 78655 T433 L P S T K I L T F Y R K Q P F
Conservation
Percent
Protein Identity: 100 N.A. 89 83.3 N.A. 92 91.6 N.A. N.A. 69.1 49.3 65.3 N.A. 24.5 42.4 24.6 N.A.
Protein Similarity: 100 N.A. 90 86 N.A. 95.5 94.7 N.A. N.A. 80.7 56.4 77.4 N.A. 38.7 60 39.5 N.A.
P-Site Identity: 100 N.A. 100 80 N.A. 80 86.6 N.A. N.A. 13.3 6.6 0 N.A. 0 26.6 6.6 N.A.
P-Site Similarity: 100 N.A. 100 86.6 N.A. 93.3 100 N.A. N.A. 33.3 26.6 53.3 N.A. 13.3 40 13.3 N.A.
Percent
Protein Identity: 29.7 N.A. N.A. 30.7 N.A. 26.5
Protein Similarity: 50.7 N.A. N.A. 49 N.A. 43.1
P-Site Identity: 6.6 N.A. N.A. 13.3 N.A. 6.6
P-Site Similarity: 33.3 N.A. N.A. 40 N.A. 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 8 0 8 0 8 0 8 50 8 8 15 8 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 15 8 8 15 8 29 15 0 8 0 8 0 0 0 8 % D
% Glu: 43 8 36 0 15 29 0 0 43 8 0 0 8 8 43 % E
% Phe: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 8 % F
% Gly: 0 0 0 0 29 0 0 15 15 0 8 0 0 0 15 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 15 8 0 0 8 22 0 0 0 0 0 15 0 0 8 % I
% Lys: 0 43 15 15 22 0 43 15 8 0 8 43 0 0 8 % K
% Leu: 15 8 0 0 0 15 8 8 0 0 0 0 8 0 0 % L
% Met: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 15 15 8 0 15 0 0 0 0 22 0 15 0 % N
% Pro: 0 8 0 22 0 0 0 15 0 0 0 0 36 15 0 % P
% Gln: 0 8 8 0 0 0 8 0 0 0 43 0 8 0 8 % Q
% Arg: 0 8 0 0 0 0 0 0 0 0 8 8 0 0 0 % R
% Ser: 8 0 8 22 8 8 0 36 0 15 8 0 8 36 0 % S
% Thr: 0 0 8 8 0 0 0 8 8 15 8 0 15 8 0 % T
% Val: 0 0 0 8 0 0 8 8 8 0 8 8 8 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 15 0 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _