Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HYOU1 All Species: 28.48
Human Site: S779 Identified Species: 48.21
UniProt: Q9Y4L1 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y4L1 NP_001124463.1 999 111335 S779 S G K L S A A S T W L E D E G
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001096142 916 102146 S696 S G K L S A A S T W L E D E G
Dog Lupus familis XP_536547 1100 121754 S779 S G R L S A A S T W L E D E G
Cat Felis silvestris
Mouse Mus musculus Q9JKR6 999 111163 S779 S G K L S A T S T W L E D E G
Rat Rattus norvegicus Q63617 999 111271 S779 S G K L S A T S T W L E D E G
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZLK7 1002 112301 S784 S K K L S E A S N W M E E E G
Frog Xenopus laevis Q566I3 646 72655 N453 H S K S L K H N K R I L F Q R
Zebra Danio Brachydanio rerio Q7ZUW2 980 110301 S760 S G R L S V A S S W M D E E G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8INI8 641 70177 T448 Y E G E R A M T K D N N A L G
Honey Bee Apis mellifera XP_624153 932 105575 T725 Y E D G F S V T A E I Y E E K
Nematode Worm Caenorhab. elegans P09446 640 69704 E447 L I Q V Y E G E R A M T K D N
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002322555 881 98313 Y676 L K N N L E G Y I Y S T K E K
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_567510 867 96706 A672 N L E S Y I Y A T K E K L E T
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa O74225 707 78655 G514 E E V K D E N G D V V M E G D
Conservation
Percent
Protein Identity: 100 N.A. 89 83.3 N.A. 92 91.6 N.A. N.A. 69.1 49.3 65.3 N.A. 24.5 42.4 24.6 N.A.
Protein Similarity: 100 N.A. 90 86 N.A. 95.5 94.7 N.A. N.A. 80.7 56.4 77.4 N.A. 38.7 60 39.5 N.A.
P-Site Identity: 100 N.A. 100 93.3 N.A. 93.3 93.3 N.A. N.A. 66.6 6.6 60 N.A. 13.3 6.6 0 N.A.
P-Site Similarity: 100 N.A. 100 100 N.A. 93.3 93.3 N.A. N.A. 80 26.6 93.3 N.A. 20 33.3 26.6 N.A.
Percent
Protein Identity: 29.7 N.A. N.A. 30.7 N.A. 26.5
Protein Similarity: 50.7 N.A. N.A. 49 N.A. 43.1
P-Site Identity: 6.6 N.A. N.A. 13.3 N.A. 0
P-Site Similarity: 13.3 N.A. N.A. 40 N.A. 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 43 36 8 8 8 0 0 8 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 8 0 8 0 0 0 8 8 0 8 36 8 8 % D
% Glu: 8 22 8 8 0 29 0 8 0 8 8 43 29 72 0 % E
% Phe: 0 0 0 0 8 0 0 0 0 0 0 0 8 0 0 % F
% Gly: 0 43 8 8 0 0 15 8 0 0 0 0 0 8 58 % G
% His: 8 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % H
% Ile: 0 8 0 0 0 8 0 0 8 0 15 0 0 0 0 % I
% Lys: 0 15 43 8 0 8 0 0 15 8 0 8 15 0 15 % K
% Leu: 15 8 0 50 15 0 0 0 0 0 36 8 8 8 0 % L
% Met: 0 0 0 0 0 0 8 0 0 0 22 8 0 0 0 % M
% Asn: 8 0 8 8 0 0 8 8 8 0 8 8 0 0 8 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 8 0 0 0 0 0 0 0 0 0 0 8 0 % Q
% Arg: 0 0 15 0 8 0 0 0 8 8 0 0 0 0 8 % R
% Ser: 50 8 0 15 50 8 0 50 8 0 8 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 15 15 43 0 0 15 0 0 8 % T
% Val: 0 0 8 8 0 8 8 0 0 8 8 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 50 0 0 0 0 0 % W
% Tyr: 15 0 0 0 15 0 8 8 0 8 0 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _