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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HYOU1
All Species:
31.21
Human Site:
T269
Identified Species:
52.82
UniProt:
Q9Y4L1
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y4L1
NP_001124463.1
999
111335
T269
R
G
V
G
F
D
R
T
L
G
G
L
E
M
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001096142
916
102146
T231
R
G
V
G
F
D
R
T
L
G
G
L
E
M
E
Dog
Lupus familis
XP_536547
1100
121754
T269
R
G
V
G
F
D
R
T
L
G
G
L
E
M
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9JKR6
999
111163
T269
R
G
V
G
F
D
R
T
L
G
G
L
E
M
E
Rat
Rattus norvegicus
Q63617
999
111271
T269
R
G
V
G
F
D
R
T
L
G
G
L
E
M
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZLK7
1002
112301
T264
Q
G
I
G
F
D
R
T
L
G
G
L
E
M
E
Frog
Xenopus laevis
Q566I3
646
72655
A60
E
S
R
R
K
T
P
A
A
I
A
L
K
E
N
Zebra Danio
Brachydanio rerio
Q7ZUW2
980
110301
T261
R
G
V
G
F
D
R
T
L
G
G
F
E
M
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8INI8
641
70177
Q55
I
G
D
P
A
K
N
Q
V
A
M
N
P
R
N
Honey Bee
Apis mellifera
XP_624153
932
105575
T260
L
G
V
G
Y
D
R
T
L
G
G
L
E
V
Q
Nematode Worm
Caenorhab. elegans
P09446
640
69704
A54
T
E
R
L
I
G
D
A
A
K
N
Q
V
A
M
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002322555
881
98313
E267
K
D
V
R
W
D
P
E
L
G
G
Q
T
M
E
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_567510
867
96706
G263
K
D
V
R
W
D
L
G
L
G
G
Q
S
M
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
O74225
707
78655
M121
T
E
L
I
A
M
F
M
S
K
I
K
Q
T
T
Conservation
Percent
Protein Identity:
100
N.A.
89
83.3
N.A.
92
91.6
N.A.
N.A.
69.1
49.3
65.3
N.A.
24.5
42.4
24.6
N.A.
Protein Similarity:
100
N.A.
90
86
N.A.
95.5
94.7
N.A.
N.A.
80.7
56.4
77.4
N.A.
38.7
60
39.5
N.A.
P-Site Identity:
100
N.A.
100
100
N.A.
100
100
N.A.
N.A.
86.6
6.6
93.3
N.A.
6.6
73.3
0
N.A.
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
N.A.
100
13.3
93.3
N.A.
13.3
93.3
0
N.A.
Percent
Protein Identity:
29.7
N.A.
N.A.
30.7
N.A.
26.5
Protein Similarity:
50.7
N.A.
N.A.
49
N.A.
43.1
P-Site Identity:
46.6
N.A.
N.A.
46.6
N.A.
0
P-Site Similarity:
60
N.A.
N.A.
60
N.A.
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
15
0
0
15
15
8
8
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
15
8
0
0
72
8
0
0
0
0
0
0
0
0
% D
% Glu:
8
15
0
0
0
0
0
8
0
0
0
0
58
8
65
% E
% Phe:
0
0
0
0
50
0
8
0
0
0
0
8
0
0
0
% F
% Gly:
0
65
0
58
0
8
0
8
0
72
72
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
8
8
8
0
0
0
0
8
8
0
0
0
0
% I
% Lys:
15
0
0
0
8
8
0
0
0
15
0
8
8
0
0
% K
% Leu:
8
0
8
8
0
0
8
0
72
0
0
58
0
0
0
% L
% Met:
0
0
0
0
0
8
0
8
0
0
8
0
0
65
8
% M
% Asn:
0
0
0
0
0
0
8
0
0
0
8
8
0
0
15
% N
% Pro:
0
0
0
8
0
0
15
0
0
0
0
0
8
0
0
% P
% Gln:
8
0
0
0
0
0
0
8
0
0
0
22
8
0
8
% Q
% Arg:
43
0
15
22
0
0
58
0
0
0
0
0
0
8
0
% R
% Ser:
0
8
0
0
0
0
0
0
8
0
0
0
8
0
0
% S
% Thr:
15
0
0
0
0
8
0
58
0
0
0
0
8
8
8
% T
% Val:
0
0
65
0
0
0
0
0
8
0
0
0
8
8
0
% V
% Trp:
0
0
0
0
15
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _